- Search results for Cay16410
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13 products were found matching "Cay16410"!
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Item number: Cay16410-1
Prostaglandin F2beta (PGF2beta) is the 9beta-hydroxy stereoisomer of PGF2alpha. It is much less active than PGF2alpha in antifertility and bronchoconstrictor activities. PGF2beta exhibits bronchodilating activity in guinea pigs and cats and antagonizes the bronchoconstrictor activity of PGF2alpha.Formal Name:...
Keywords: | 9beta-PGF2alpha, PGF2beta, 9beta,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 4510-16-1 |
MW: | 354.5 D |
From 113.00€
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Item number: Cay11164-100
5-Azacytidine, a chemical analogue of the DNA and RNA nucleoside cytidine, is an inhibitor of DNA methyltransferases, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes (IC50s = 2.4 and 2.6 µM for in vitro anti-myeloma...
Keywords: | 5-AzaC, Antibiotic U 18496, Ladakamycin, Mylosar, NSC 102816, NSC 103-627, U 18496, WR 183027,... |
Application: | DNA methyltransferase inhibitor |
CAS | 320-67-2 |
MW: | 244.2 D |
From 27.00€
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Item number: Cay16644-10
Porcupine (PORCN) is a membrane bound O-acyltransferase that mediates palmitoylation of Wnt family proteins. This step is required for secretion and biologic activity of Wnt proteins, which have roles in embryonic development and cancer. Wnt-C59 is a potent inhibitor of PORCN, as measured by prevention of Wnt3A...
Keywords: | PORCN Inhibitor II, 4-(2-methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]-benzeneacetamide |
Application: | Porcupine inhibitor |
CAS | 1243243-89-1 |
MW: | 379.5 D |
From 60.00€
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Item number: Cay16664-10
Mozavaptan is an orally bioavailable antagonist of vasopressin V2 receptors (Ki = 9.42 nM in HeLa cells expressing the human receptor). It is selective for vasopressin V2 over V1 receptors (IC50s = 14 and 1,200 nM, respectively) in radioligand binding assays using rat kidney and rat liver membranes that endogenously...
Keywords: | OPC 31260, N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-benzamide,... |
Application: | Arginine vasopressin receptor 2 (AVPR2) antagonist |
CAS | 138470-70-9 |
MW: | 464 D |
From 48.00€
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Item number: Cay16421-10
AB-CHMINACA (Cay-15434) is an indazole-based synthetic cannabinoid (CB) that is structurally related to AB-FUBINACA (Cay-14039), a high affinity ligand of the CB1 receptor (Ki = 0.9 nM). AB-CHMINACA metabolite M2 is a potential derivative resulting from the replacement of a terminal amide NH2 with a hydroxyl group....
Keywords: | AMB N-methylcyclohexyl analog, AMB-CHMINACA, MAB-AB-CHMINACA, MMB-CHMINACA,... |
Application: | Analytical reference standard, Potential synthetic cannabinoid AB-CHMINACA metabolite |
CAS | 1971007-96-1 |
MW: | 371.5 D |
From 60.00€
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Item number: Cay16437-10
3-desoxy-3,4-MDPV is an analog of 3,4-MDPV in which the heterocyclic 3-position oxygen from the 3,4-methylenedioxy ring has been replaced by a methylene bridge. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.Formal Name:...
Keywords: | 3-desoxy-3,4-MDPV, 5-DBFPV, 5-dihydrobenzofuran Pyrovalerone,... |
Application: | Analytical reference standard, 3,4-MDPV analog |
CAS | 2117405-33-9 |
MW: | 309.8 D |
From 98.00€
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Item number: Cay16439-10
Lysine-specific demethylase 1 (LSD1) belongs to the family of flavin adenine dinucleotide (FAD)-dependent amine oxidases that include monoamine oxidases (MAOs) and polyamine oxidase (PAO). LSD1 specifically demethylates mono- and dimethylated histone H3 lysine 4, resulting in transcriptional repression. It also...
Keywords: | rel-N-[(1R,2S)-2-phenylcyclopropyl]-4-piperidinamine, dihydrochloride |
Application: | Irreversible LSD1 inhibitor |
CAS | 2102933-95-7 |
MW: | 289.2 D |
From 43.00€
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Item number: Cay16464-10
alpha-D-Glucose-1,6-bisphosphate is a bis-phosphorylated derivative of alpha-D-glucose that has roles in carbohydrate metabolism. It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate. It is...
Keywords: | D-Glucose-1,6-diphosphate, Glc-1,6-P2, alpha-D-glucopyranose, 1,6-bis(dihydrogen phosphate), cyclohexanamine (1:4), hydrate |
Application: | alpha-/beta-phosphoglucomutase / hexoglucomutase identification, differentiation, characterization |
MW: | 736.8 D |
From 60.00€
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Item number: Cay16441-10
SMYD2 is a lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53 and retinoblastoma-associated protein. LLY-507 is a cell-active, small molecule inhibitor of SMYD2 (IC50 = 15 nM). It has been shown to inhibit p53 lysine370 monomethylation in KYSE-150 esophageal squamous...
Keywords: | 5-cyano-2'-[4-[2-(3-methyl-1H-indol-1-yl)ethyl]-1-piperazinyl]-N-[3-(1-pyrrolidinyl)propyl]-[1,1'-biphenyl]-3-carboxamide |
Application: | SMYD2 inhibitor |
CAS | 1793053-37-8 |
MW: | 574.8 D |
From 77.00€
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Item number: Cay16419-10
In humans, two forms of diacylglycerol lipase, DAGLalpha and DAGLbeta, generate the endocannabinoid 2-arachidonoyl glycerol (2-AG, Cay-62160) by attacking DAG at the sn-1 position. LEI-106 is a potent in vitro inhibitor of sn-1 DAGLalpha (IC50 = 18 nM). It blocks the hydrolysis of sn-1-oleoyl-2-AG, the natural...
Keywords: | N-[(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)sulfonyl]-N-[(4-phenoxyphenyl)methyl]-glycine |
Application: | DAGLalpha inhibitor |
CAS | 1620582-23-1 |
MW: | 481.6 D |
From 61.00€
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Item number: Cay16484-10
Zilpaterol is a beta-adrenergic receptor agonist that putatively through activation of protein kinase A increases protein synthesis in skeletal muscle fibers, as well as reduces lipogenesis and increases lipolysis in adipose tissues. It was approved by the FDA in 2006 as a veterinary food additive for the purpose of...
Keywords: | RU-42173, (6R,7R)-rel-4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]-imidazo[4,5,1-jk][1]benzazepin-2(1H)-one,... |
Application: | beta-adrenergic receptor agonist |
CAS | 119520-06-8 |
MW: | 297.8 D |
From 60.00€
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Item number: Cay16414-10
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a tobacco-specific nitrosamine carcinogen. Reactive metabolites of NNK alkylate DNA, forming pyridyloxobutyl (POB) and pyridylhydroxybutyl (PHB) adducts, and induce DNA methylation. NNK (100 mg/kg, single dose) increases the protein levels of DNA...
Keywords: | NNK, 4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone |
Application: | Tobacco-specific nitrosamine carcinogen |
CAS | 64091-91-4 |
MW: | 207.2 D |
From 115.00€
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