- Search results for Cay16130
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8 products were found matching "Cay16130"!
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Item number: Cay16130-5
Prostaglandin F2alpha (PGF2alpha) 1,9-lactone is a lipid-soluble internal ester of PGF2alpha. It is resistant to hydrolysis by human plasma esterases even after incubation for 20 hours under physiological conditions. PGF2alpha 1,9-lactone exhibits little antifertility and vasoactivity compared to PGF2alpha.Formal...
Keywords: | PGF2alpha 1,9-lactone, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, 1,9-lactone |
Application: | Bioactive lipid assays |
CAS | 55314-48-2 |
MW: | 336.5 D |
From 117.00€
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Item number: Cay16134-10
Bisphosphonates bind strongly to bone and reduce bone resorption through effects on both osteoclasts and osteoblasts. Clodronate is a non-nitrogenous bisphosphonate that has been used in the treatment of osteoporosis and other metabolic bone diseases. It binds to hydroxyapatite crystals with an affinity constant of...
Keywords: | Clodronic acid, P,P'-(dichloromethylene)bis-phosphonic acid, disodium salt, tetrahydrate |
Application: | Non-nitrogenous bisphosphonate, hydroxyapatite crystal growth inhibitor |
CAS | 88416-50-6 |
MW: | 360.9 D |
From 50.00€
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Item number: Cay16136-50
Sotalol is a non-selective antagonist of beta-adrenergic receptors (beta-ARs, IC50s = 8.9 and 5.2 µM for beta1- and beta2-ARs, respectively) and a class III antiarrhythmic agent. It decreases delayed outward potassium currents (IK) in guinea pig ventricular cells and prolongs action potential duration in...
Keywords: | (±)-Sotalol, DL-Sotalol, MJ1999, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-methanesulfonamide, monohydrochloride |
Application: | beta1/2-adrenergic receptor antagonist |
CAS | 959-24-0 |
MW: | 308.8 D |
From 43.00€
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Item number: Cay16138-10
trans-Clovamide is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.). It has antioxidant and antiradical properties and has shown neuroprotective effects (EC50s = 0.9-3.7 µM) in several in vitro models of neuronal death.Formal Name:...
Keywords: | N-trans-Caffeoyl-L-DOPA, N-[3',4'-Dihydroxy-(E)-cinnamoyl]-3-hydroxy-L-tyrosine,... |
Application: | Antioxidant |
CAS | 53755-02-5 |
MW: | 359.3 D |
From 127.00€
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Item number: Cay16133-50
Procarbazine is a methyl hydrazine derivative that is converted by metabolism into a methylating species which converts DNA to various DNA adducts, including O6-methylguanine. While this process is mutagenic and carcinogenic, procarbazine is used with the compounds mechlorethamine, vincristine, also known as oncovin...
Keywords: | Indicarb, Matulane(R), Natulan, NSC 77213, N-(1-methylethyl)-4-[(2-methylhydrazinyl)methyl]-benzamide, monohydrochloride |
Application: | Antineoplastic, DNA methylation |
CAS | 366-70-1 |
MW: | 257.8 D |
From 43.00€
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Item number: Cay16139-50
Pyronaridine is an antimalarial agent. It is active against six P. falciparum drug-sensitive or -resistant strains (IC50s = 1.53-3.94 nM). Pyronaridine (3, 6, and 8 mg/kg) in combination with artesunate (Cay-11817) reduces parasitemia in P. chabaudi-infected mice. It inhibits the replication of severe acute...
Keywords: | PND, 4-[(7-chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)-phenol, tetraphosphate |
Application: | Antimalarial compound |
CAS | 76748-86-2 |
MW: | 910 D |
From 92.00€
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Item number: Cay16137-10
Isofagomine (D-tartrate) is a competitive inhibitor of human lysosomal beta-glucosidase (Ki = 0.016-0.025 µM, IC50 = 0.06 µM). By interacting with the catalytic pocket of beta-glucosidase it acts as a chemical chaperone that increases the amount of beta-glucosidase by stabilizing and/or promoting the folding of the...
Keywords: | 5R-(hydroxymethyl)-3R,4R-piperidinediol, mono 2S,3S-dihydroxybutanedioate |
Application: | Competitive glucosylceramidase (GBA) inhibitor |
CAS | 957230-65-8 |
MW: | 297.3 D |
From 109.00€
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Item number: Cay16135-50
Phentolamine is a reversible antagonist of alpha-adrenergic receptors, non-specifically binding all alpha1- and alpha2-adrenoceptors with nanomolar affinities. Formulations containing phentolamine have been used in the treatment of hypertensive emergencies, as well as chronic and emergent pain.Formal Name:...
Keywords: | 3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-phenol, monomethanesulfonate |
Application: | alpha1/2-adrenergic receptor antagonist |
CAS | 65-28-1 |
MW: | 377.5 D |
From 60.00€
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