- Search results for Cay160750
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11 products were found matching "Cay160750"!
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Item number: Cay16077-500
NAD+, known more formally as nicotinamide adenine dinucleotide, is a signaling molecule as well as a cofactor or substrate for many enzymes. It acts as an oxidizing agent, accepting electrons from other molecules while being converted to its reduced form, NADH (Cay-16078). NAD+ is also essential for the activity of...
Keywords: | Nicotinamide adenine dinucleotide, adenosine 5'-(trihydrogen diphosphate), P'->5'-ester with... |
Application: | Oxidizing agent |
CAS | 53-84-9 |
MW: | 663.4 D |
From 60.00€
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Item number: Cay160750-1
TNF-related apoptosis-inducing ligand (TRAIL) is a protein encoded by the TNFSF10 gene in humans and is a member of the TNF superfamily of proteins. TRAIL contains an N-terminal cytoplasmic domain, a transmembrane domain, and a C-terminal extracellular receptor binding domain. It is produced in immune effector cells...
Keywords: | Apo-2L, Apo-2 Ligand, CD253, TNF Ligand Superfamily Member 10, TNFSF10 |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay16072-50
Pheophorbide a is a product of chlorophyll breakdown that has been used as a photosensitizer in photodynamic therapy for the treatment of cancer. It has been reported to inhibit U87MG cells with an IC50 value of 2.8 µg/ml and demonstrates cytostatic activity specifically against glioblastoma cells without affecting...
Keywords: | 2-Deacetyl-2-vinylbacteriopheophorbide,... |
Application: | Chlorophyll breakdown product, Photosensitizer |
CAS | 15664-29-6 |
MW: | 592.7 D |
From 92.00€
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Item number: Cay16075-10
Cefpodoxime is a metabolite of cefpodoxime proxetil, a third generation cephalosporin antibiotic, that is active against both Gram-positive and Gram-negative bacteria (MIC90s = 0.015-8 µg/ml).Formal Name:...
Keywords: | R 3763,... |
Application: | Antibiotic |
CAS | 80210-62-4 |
MW: | 427.5 D |
From 43.00€
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Item number: Cay16071-50
Raltegravir is an orally bioavailable inhibitor of HIV-1 integrase (IC50 = 15 nM in a strand transfer assay). It inhibits the spread of HIV-1IIIb infection in MT-4 cell culture with 95% cell culture inhibitory concentration (CIC95) values of 19 and 31 nM in medium containing 10% heat-inactivated fetal bovine serum...
Keywords: | MK-0518,... |
Application: | HIV integrase inhibitor |
CAS | 871038-72-1 |
MW: | 482.5 D |
From 66.00€
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Item number: Cay16070-250
Oseltamivir is an antiviral prodrug targeted against the influenza viruses. Once hydrolyzed in the liver to its active metabolite, oseltamivir acid (Cay-15779), it can competitively inhibit viral neuraminidase (IC50s = 0.1-4.9 nM for influenza neuraminidases A and B), blocking the release of new viral particles from...
Keywords: | GS-4104, Ro 64-0796/002, Tamiflu(R), 4R-(acetylamino)-5S-amino-3R-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid, ethyl... |
Application: | Antiviral prodrug, influenzavirus A, B neuraminidase inhibitor |
CAS | 204255-11-8 |
MW: | 410.4 D |
From 66.00€
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Item number: Cay16707-50
Baricitinib is an inhibitor of JAK1 and JAK2 (IC50s = 0.0059 and 0.0057 µM, respectively). It is selective for JAK1 and JAK2 over JAK3, TYK2, c-Met, and checkpoint kinase 2 (Chk2, IC50s = >0.4, 0.053, >10, and >1 µM, respectively). Baricitinib inhibits IL-6-induced phosphorylation of STAT3 in isolated human...
Keywords: | INCB 028050, LY3009104, 1-(ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile |
Application: | JAK1 / JAK2 inhibitor |
CAS | 1187594-09-7 |
MW: | 371.4 D |
From 50.00€
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Item number: Cay21607-50
Benidipine is an orally bioavailable blocker of L-, T-, and N-type calcium channels. In guinea pig ventricular cells benidipine has an IC50 of 2.7 nM for calcium currents, determined using whole cell voltage clamp electrophysiology. It prevents oxidative stress dose-dependently in vitro, decreases blood pressure in...
Keywords: | (±)-Benidipine, KW-3049, (4R)-rel-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-methyl... |
Application: | Calcium channel blocker |
CAS | 91599-74-5 |
MW: | 542 D |
From 50.00€
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Item number: Cay18607-50
Organophosphates inactivate acetylcholinesterase (AChE) by reacting covalently with the active center serine, thus inhibiting its action of hydrolyzing acetylcholine at central and peripheral synapses. Acetylcholine accumulation results in an over-stimulation of cholinergic receptors, which can disrupt numerous...
Keywords: | HI-6, 1-[[[4-(aminocarbonyl)pyridinio]methoxy]methyl]-2-[(hydroxyimino)methyl]-pyridinium, dichloride |
Application: | AChE reactivator |
CAS | 34433-31-3 |
MW: | 359.2 D |
From 66.00€
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Item number: Cay16067-50
(±)-Muscone is an odoriferous constituent of musk, a glandular secretion originally collected from the male musk deer, that has found use both in the composition of perfumes and in traditional Chinese medicine practices. (±)-Muscone has been shown to exhibit anti-inflammatory effects by reducing the expression of...
Keywords: | 3-Methylcyclopentadecanone, 3-methyl-cyclopentadecanone |
Application: | Antiinflammatory, odor |
CAS | 541-91-3 |
MW: | 238.4 D |
From 60.00€
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Item number: Cay16807-50
(S)-(+)-Methoprene is a widely used insect growth regulator. It is remarkable for its lack of significant effects against a wide variety of mammals, although concerns remain for its effects on arthropod development. Methoprene acts as an activator of the juvenile hormone receptor, known as Methoprene-tolerant or Met...
Keywords: | Altosid(TM), d-Methoprene, ZR 2458, 11-methoxy-3,7S,11-trimethyl-2E,4E-dodecadienoic acid, 1-methylethyl ester |
Application: | TcMet activator, insect growth regulator |
CAS | 65733-16-6 |
MW: | 310.5 D |
From 43.00€
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