- Search results for Cay16050
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13 products were found matching "Cay16050"!
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Item number: Cay16050-1
1a,1b-dihomo Prostaglandin F2alpha (1a,1b-dihomo PGF2alpha) is the theoretical product of adrenic acid in the COX pathway. 1a,1b-dihomo PGF2alpha is primarily produced in renal medulla where adrenic acid is selectively distributed.Formal Name: 9alpha,11alpha,15S-trihydroxy-1a,1b-dihomo-prosta-5Z,13E-dien-1-oic acid....
Keywords: | 1a,1b-dihomo PGF2alpha, 9alpha,11alpha,15S-trihydroxy-1a,1b-dihomo-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 57944-39-5 |
MW: | 382.5 D |
From 90.00€
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Item number: Cay11160-50
D2PM (hydrochloride) is a psychoactive designer drug that has recently been demonstrated to have toxic effects in humans. D2PM is also used in organic synthesis to prepare the Corey-Bakshi-Shibata catalyst. This product is intended for forensic purposes.Formal Name: alpha,alpha-diphenyl-2R-pyrrolidinemethanol,...
Keywords: | Diphenyl-2-pyrrolidinemethanol, Diphenylprolinol, alpha,alpha-diphenyl-2R-pyrrolidinemethanol, monohydrochloride |
Application: | Analytical reference standard, psychoactive designer drug, Corey-Bakshi-Shibata catalyst synthesis |
CAS | 172152-19-1 |
MW: | 289.8 D |
From 84.00€
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Item number: Cay11600-50
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. GDC-0941 is a potent pan inhibitor of class I catalytic subunits of PI3K, inhibiting p110alpha, beta, delta, and gamma with IC50 values of 3, 33, 3, and 75 nM, respectively. It is much less...
Keywords: | GNE-0941, Pictilisib, Pictrelisib,... |
Application: | PI3K inhibitor |
CAS | 957054-30-7 |
MW: | 513.6 D |
From 180.00€
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Item number: Cay11660-50
Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC50s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC50 = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35%...
Keywords: | AL 4862, 4R-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-1,1-dioxide-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide |
Application: | Carbonic anhydrases inhibitor |
CAS | 138890-62-7 |
MW: | 383.5 D |
From 44.00€
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Item number: Cay160500-1
Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position yielding a free fatty acid and a lysophospholipid. The release of arachidonic acid from membrane phospholipids by PLA2 is believed to be a key step in the control of eicosanoid production within the cell. Human synovial sPLA2 is a...
Keywords: | Anti-PLA2B, Anti-PLA2G2A, Anti-NPS-PLA2, Anti-NPS-PLA2, Anti-GIIC sPLA2, Anti-GIIC sPLA2, Anti-Group IIA phospholipase A2,... |
Application: | IP, WB |
Host: | Mouse |
Species reactivity: | human |
422.00€
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Item number: Cay160507-1
Calcium-independent phospholipase A2 (iPLA2) is one of the most recently characterized isoforms in the growing list of the phospholipase A2 enzyme family. iPLA2 has been purified or cloned from CHO cells and mouse P388D1 macrophage-like cells and is the major isoform of phospholipase A2 found in A-10 smooth muscle...
Keywords: | Anti-PLA2G6, Anti-PLPLA9, Anti-PNPLA9, Anti-PNPLA9, Anti-CaI-PLA2, Anti-GVI PLA2, Anti-CaI-PLA2, Anti-GVI PLA2,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, bovine, hamster, rat |
422.00€
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Item number: Cay160502-1
sPLA2 catalyzes the hydrolysis of phospholipids at the sn-2 position yielding a free fatty acid and a lysophospholipid. The release of arachidonic acid from membrane phospholipids by PLA2 is believed to be a key step in the control of eicosanoid production within the cell. Human sPLA2 (Type IIA) is secreted, 14 kDa...
Keywords: | Anti-PLA2B, Anti-PLA2G2A, Anti-NPS-PLA2, Anti-NPS-PLA2, Anti-GIIC sPLA2, Anti-GIIC sPLA2, Anti-Group IIA phospholipase A2,... |
Application: | IHC, IP, WB |
Host: | Rabbit |
Species reactivity: | human, rat |
422.00€
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Item number: Cay16071-50
Raltegravir is an orally bioavailable inhibitor of HIV-1 integrase (IC50 = 15 nM in a strand transfer assay). It inhibits the spread of HIV-1IIIb infection in MT-4 cell culture with 95% cell culture inhibitory concentration (CIC95) values of 19 and 31 nM in medium containing 10% heat-inactivated fetal bovine serum...
Keywords: | MK-0518,... |
Application: | HIV integrase inhibitor |
CAS | 871038-72-1 |
MW: | 482.5 D |
From 66.00€
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Item number: Cay16042-50
Cinacalcet is a calcimimetic and an allosteric agonist of the calcium-sensing receptor (CaSR, EC50 = 79.4 nM in HEK293T cells expressing the human receptor). In vivo, cinacalcet (0.1-10 mg/kg, s.c.) decreases plasma levels of parathyroid hormone (PTH) in rats. It also decreases plasma levels of PTH and parathyroid...
Keywords: | AMG 073, KRN 1493, Mimpara, alphaR-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, monohydrochloride |
Application: | Calcimimetic |
CAS | 364782-34-3 |
MW: | 393.9 D |
From 109.00€
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Item number: Cay16025-50
PHTPP is a pyrazolo[1,5-alpha]pyrimidine-based ligand that acts as a full antagonist of estrogen ERbeta receptors with 36-fold selectivity over ERalpha. It exhibits no significant agonism on ERalpha or ERbeta. This compound has been used to selectively target ERbeta in the study of the opposing effects of hormone...
Keywords: | 4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-phenol |
Application: | Erbeta antagonist |
CAS | 805239-56-9 |
MW: | 423.3 D |
From 130.00€
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Item number: Cay16024-50
Tomatine is a steroidal saponin that has been found in S. lycopersicum and has diverse biological activities. It is active against a panel of 19 plant pathogenic fungi (EC50s = 13-912 µM) and inhibits the growth of L. amazonensis promastigotes (IC50 = 124 nM). Tomatine (0.75, 1, and 1.5 µM) inhibits autophagy and...
Keywords: | Lycopersicin, NSC 234440, NSC 9223, alpha-Tomatine, (3beta,5alpha,22beta,25S)-spirosolan-3-yl... |
Application: | Bioactive steroidal saponin |
CAS | 17406-45-0 |
MW: | 1034.2 D |
From 77.00€
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Item number: Cay160150-1
Prostaglandin E synthase (PGES) catalyzes the isomerization of PGH2 (Cay-17020) to PGE2 (Cay-14010). Cytosolic and microsomal PGES enzymes have been cloned and characterized. Cytosolic PGES (cPGES) is a glutathione-dependent enzyme with a predicted size of 18.6 kDa (23 kDa on SDS-PAGE). The enzyme is expressed in a...
Keywords: | Anti-P23, Anti-cPGES, Anti-cPGES, Anti-PTGES3, Anti-Hsp90 co-chaperone, Anti-Hsp90 co-chaperone, Anti-Prostaglandin E... |
Application: | WB |
Host: | Rabbit |
422.00€
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