2 products were found matching "Cay160402-%25"!

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Item number: Cay16042-25

Cinacalcet is a calcimimetic and an allosteric agonist of the calcium-sensing receptor (CaSR, EC50 = 79.4 nM in HEK293T cells expressing the human receptor). In vivo, cinacalcet (0.1-10 mg/kg, s.c.) decreases plasma levels of parathyroid hormone (PTH) in rats. It also decreases plasma levels of PTH and parathyroid...

Keywords:	AMG 073, KRN 1493, Mimpara, alphaR-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, monohydrochloride
Application:	Calcimimetic
CAS	364782-34-3
MW:	393.9 D

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Tetrahydrouridine

Item number: Cay16402-25

Tetrahydrouridine is an inhibitor of cytidine deaminase (Kis = 54 and 240 nM for the human and E. coli enzymes, respectively). In vivo, tetrahydrouridine inhibits the metabolism of decitabine (Cay-11166) and enhances decitabine-induced inhibition of tumor growth in a B16 murine melanoma model.Formal Name:...

Keywords:	NSC 112907, THU, 3,4,5,6-tetrahydro-uridine
Application:	Competitive, reversible cytidine deaminase inhibitor
CAS	18771-50-1
MW:	248.2 D

From 218.00€ *

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