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(±)5-iPF2alpha-VI
(±)5-iPF2alpha-VI

Item number: Cay16300-25

Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. (±)5-iPF2alpha-VI is one of dozens of possible stereo- and regioisomeric...
Keywords: 5-iso PGF2alpha-VI, 5-iso Prostaglandin F2alpha-VI, iPF2alpha-I, Isoprostane F2alpha-I,...
Application: Bioactive lipid assays
CAS 179094-11-2
MW: 354.5 D
From 80.00€ *
Review
TC-O 9311
TC-O 9311

Item number: Cay14030-25

TC-O 9311 is an agonist of the orphan G protein-coupled receptor GPR139 (EC50 = 39 nM in a calcium mobilization assay). It is selective for GPR139 over a panel of 90 additional targets. TC-O 9311 (1 µM) inhibits cell death induced by 1-methyl-4-phenylpyridinium (MPP+), but not 6-hydroxydopamine (6-OHDA, Cay-25330),...
Keywords: 3,5-dimethoxy-benzoic acid, 2-[(1-naphthalenylamino)carbonyl]hydrazide
Application: Potent GPR139 agonist
CAS 444932-31-4
MW: 365.4 D
From 43.00€ *
Review
NSC 146109 (hydrochloride)
NSC 146109 (hydrochloride)

Item number: Cay16430-25

NSC 146109 is an activator of the tumor suppressor p53 that increases expression of p53 and the p53 target DR5 in wild-type and p53-knockout HCT116 colon adenocarcinoma cells. It is selective for p53, having no effect on p73 expression in HCT116 cells at a concentration of 2 µM. NSC 146109 activates p53, which...
Keywords: XI-011, carbamimidothioic acid, (10-methyl-9-anthracenyl)methyl ester, monohydrochloride
Application: p53 activator
CAS 59474-01-0
MW: 316.8 D
From 98.00€ *
Review