9 products were found matching "Cay16030"!

PGF2alpha isopropyl ester is an ester prodrug of PGF2alpha with enhanced lipid solubility. Due to better membrane penetration, PGF2alpha isopropyl ester is more suitable than PGF2alpha or PGF2alpha tromethamine salt for topical application in studies on intraocular pressure. The ester functionality is readily...

Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.Formal...

CD2665 is a selective retinoic acid receptor (RAR)beta and RARgamma antagonist (Kds = 110, 306, and > 2,250 nM for RARgamma, RARbeta, and RARalpha, respectively, with no binding at RXRalpha). At 10-7 M, it has been used to abrogate retinoic acid (Cay-11017)-induced antiproliferative and antidifferentiative effects...

Prostaglandin F2alpha (PGF2alpha) dimethyl amide is a weak FP receptor antagonist. In gerbil colon, PGF2alpha dimethyl amide at a dose of 3.2 µg/ml inhibits the contractile effects of PGF2alpha (at 6 ng/ml) by 50%.Formal Name: N,N-dimethyl-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide. CAS Number:...

Prostaglandin F2alpha dimethyl amine (PGF2alpha dimethyl amine) is a derivative of PGF2alpha which was designed as a PG antagonist for in vitro and in vivo studies. PGF2alpha dimethyl amine is a weak FP receptor antagonist. In gerbil colon, PGF2alpha dimethyl amine at a dose of 3.2 µg/ml inhibits the contractile...

XCT790 is an inverse agonist of estrogen-related receptor alpha (ERRalpha, IC50 = ~300-500 nM). It demonstrates 90-100% inhibition of ERRalpha constitutive activity and has no significant activity at related nuclear receptors at 10 µM. XCT790 associates with the ligand-binding domain of ERRalpha and blocks...

Jacaric acid is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants. Structurally, it is an 18-carbon omega-6 triene isomer of gamma-linolenic acid (Cay-90220). Jacaric acid induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 = 1-5 µM). It increases the...

PGI synthase (PGIS) catalyzes the conversion of PGH2 to PGI2 (prostacyclin). Human lung PGIS is a 56 kDa protein. The cloned bovine and human enzymes contain 500 amino acids and have a calculated molecular mass of 56,629 and 57,103, respectively. There is 88% homology between human and bovine PGIS.Synonyms: PGI...

Sodium stibogluconate is a pentavalent antimony derivative that is highly active against Leishmania amastigotes in macrophages. Sodium stibogluconate has diverse effects on both this intracellular parasite and its host cell.Formal Name: 2,4:2',4'-O-(oxydistibylidyne)bis-D-gluconic acid, trisodium salt, nonahydrate....