- Search results for Cay160110
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28 products were found matching "Cay160110"!
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Item number: Cay160110-1
Cyclooxygenase 1 (COX-1) is a bifunctional enzyme that exhibits both COX and peroxidase activities. It is composed of an N-terminal signal peptide, an EGF-like domain, a membrane binding domain, a catalytic domain, and a C-terminal tail. COX-1 is constitutively expressed in the gastrointestinal tract, kidney,...
Keywords: | Anti-COX1, Anti-PTGS1, Anti-COX-1, Anti-PHS 1, Anti-COX-1, Anti-PHS 1, Anti-PGHS-1, Anti-PGHS-1, Anti-PGH synthase 1,... |
Application: | WB |
Host: | Mouse |
Species reactivity: | human, ovine, bovine, rat, murine |
456.00€
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Item number: Cay16010-5
Prostaglandin F2alpha (PGF2alpha) is a widely distributed PG occurring in many species. It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity. PGF2alpha exerts its receptor mediated physiological activity at 50-100 nM. Maximal ovine...
Keywords: | Dinoprost, PGF2alpha, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 551-11-1 |
MW: | 354.5 D |
From 50.00€
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Item number: Cay11160-10
D2PM (hydrochloride) is a psychoactive designer drug that has recently been demonstrated to have toxic effects in humans. D2PM is also used in organic synthesis to prepare the Corey-Bakshi-Shibata catalyst. This product is intended for forensic purposes.Formal Name: alpha,alpha-diphenyl-2R-pyrrolidinemethanol,...
Keywords: | Diphenyl-2-pyrrolidinemethanol, Diphenylprolinol, alpha,alpha-diphenyl-2R-pyrrolidinemethanol, monohydrochloride |
Application: | Analytical reference standard, psychoactive designer drug, Corey-Bakshi-Shibata catalyst synthesis |
CAS | 172152-19-1 |
MW: | 289.8 D |
From 84.00€
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Item number: Cay11600-10
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. GDC-0941 is a potent pan inhibitor of class I catalytic subunits of PI3K, inhibiting p110alpha, beta, delta, and gamma with IC50 values of 3, 33, 3, and 75 nM, respectively. It is much less...
Keywords: | GNE-0941, Pictilisib, Pictrelisib,... |
Application: | PI3K inhibitor |
CAS | 957054-30-7 |
MW: | 513.6 D |
From 180.00€
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Item number: Cay16000-10
Fosmidomycin is an antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces that inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Fosmidomycin is active against both Gram-negative and Gram-positive bacteria and the human malarial...
Keywords: | Antibiotic FR31564, FR31564, P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt |
Application: | Antibiotic, DOXP reductoisomerase inhibitor |
CAS | 66508-37-0 |
MW: | 205.1 D |
From 60.00€
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Item number: Cay16660-10
13,14-dihydro Prostaglandin F2alpha (13,14-dihydro PGF2alpha) is the analog of PGF2alpha which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2alpha. The ED50 value for 13,14-dihydro PGF2alpha as a luteolytic agent in hamsters is 1.5 µg/100...
Keywords: | 13,14-dihydro PGF2alpha, 9alpha,11alpha,15S-trihydroxy-prost-5Z-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 27376-74-5 |
MW: | 356.5 D |
From 66.00€
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Item number: Cay11660-100
Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC50s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC50 = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35%...
Keywords: | AL 4862, 4R-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-1,1-dioxide-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide |
Application: | Carbonic anhydrases inhibitor |
CAS | 138890-62-7 |
MW: | 383.5 D |
From 44.00€
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COVID-19 Research
Item number: Cay16018-10
Camostat is a protease inhibitor. It inhibits trypsin (Ki = 1 nM), as well as various inflammatory proteases, including plasmin, kallikrein, and thrombin. Camostat (50 µM) inhibits entry of vesicular stomatitis virus (VSV) particles pseudotyped with severe acute respiratory syndrome coronavirus (SARS-CoV) and...
Keywords: | Foipan, FOY 305, 4-[[4-[(aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic acid, 2-(dimethylamino)-2-oxoethyl ester,... |
Application: | Serine protease inhibitor |
CAS | 59721-29-8 |
MW: | 494.5 D |
From 43.00€
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Item number: Cay16013-10
Prostaglandin F2alpha ethanolamide (PGF2alpha-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. AEA can be metabolized directly by the sequential action of COX-2 and specific PG synthases to produce ethanolamide...
Keywords: | Dinoprost Ethanolamide, PGF2alpha-EA, N-(2-hydroxyethyl)-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide |
Application: | Bioactive lipid assays |
CAS | 353787-70-9 |
MW: | 397.5 D |
From 96.00€
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Item number: Cay16016-10
Prostaglandin F2alpha ethyl amide (PGF2alpha-NEt) is an analog of PGF2alpha in which the C-1 carboxyl group has been modified to an N-ethyl amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs....
Keywords: | Dinoprost ethyl amide, PGF2alpha-NEt, N-ethyl-9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-amide |
Application: | Bioactive lipid assays |
CAS | 54130-36-8 |
MW: | 381.6 D |
From 73.00€
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Item number: Cay16012-10
Prostaglandin F2alpha alcohol (PGF2alpha-OH) is an analog of PGF2alpha in which the C-1 carboxyl group has been reduced to a primary alcohol. Biological studies on rat uterus show it to be a weak agonist. The compound is reported to retain ocular hypotensive properties, but the nature of the receptors which mediate...
Keywords: | AGN 190190, PGF2alpha-OH, ZK 62717, 1,9alpha,11alpha,15S-tetrahydroxyprosta-5Z,13E-diene |
Application: | Bioactive lipid assays |
CAS | 13261-27-3 |
MW: | 340.5 D |
From 72.00€
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Item number: Cay16014-10
Prostaglandin F2alpha alcohol methyl ether (PGF2alpha-OMe) is an analog of PGF2alpha in which the C-1 carboxyl group has been replaced an O-methyl ether. The compound is reported to retain ocular hypotensive properties, but the receptors which mediate this activity have not been clearly documented.Formal Name:...
Keywords: | AGN 191129, PGF2alpha-OMe, 1-methoxy-9alpha,11alpha,15S-trihydroxyprosta-5Z,13E-diene |
Application: | Bioactive lipid assays |
CAS | 143656-18-2 |
MW: | 354.5 D |
From 86.00€
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