- Search results for Cay160109-%25
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4 products were found matching "Cay160109-%25"!
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Item number: Cay16019-25
Zalcitabine is a nucleoside reverse transcriptase inhibitor (NRTI). It is phosphorylated intracellularly to its active form zalcitabine-5'-triphosphate by the successive actions of deoxycytidine kinase, deoxycytidine monophosphate kinase, and nucleoside diphosphate kinase. Zalcitabine reduces the replication of...
Keywords: | 2',3'-Dideoxycytidine, ddC, Hivid, NSC 606170, Ro 24-2027/000, 2',3'-dideoxy-cytidine |
Application: | Nucleoside reverse transcriptase inhibitor |
CAS | 7481-89-2 |
MW: | 211.2 D |
From 43.00€
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Item number: Cay16109-25
TIC10 induces the expression of TNF-related apoptosis-inducing ligand (TRAIL) at 1-5 µM in a p53-independent manner. It is orally active, stable, and crosses the blood-brain barrier. The induction of TRAIL results from dual inhibition of Akt and ERK1/2 combined with nuclear translocation of the transcription factor...
Keywords: | ONC201, 2,4,6,7,8,9-hexahydro-4-[(2-methylphenyl)methyl]-7-(phenylmethyl)-imidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one |
Application: | TRAIL expression inducer |
CAS | 1616632-77-9 |
MW: | 386.5 D |
From 43.00€
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Item number: Cay16009-25
Salmeterol is a long-acting beta2-adrenergic receptor agonist (beta2-AR, EC50s = 0.79, 63.1, and 9.4 nM for beta2-, beta1-, and beta3-ARs, respectively). It inhibits electrically-stimulated contraction of isolated guinea pig trachea strips (EC50 = 2.51 nM) and histamine-induced bronchoconstriction in guinea pigs via...
Keywords: | GR-33343G, 4-hydroxy-alpha1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol,... |
Application: | beta2-adrenergic receptor agonist |
CAS | 94749-08-3 |
MW: | 603.8 D |
From 147.00€
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Item number: Cay16001-25
Roseoflavin is an analog of flavin mononucleotide (FMN) and riboflavin that is synthesized by the soil bacterium S. davawensis and possesses antimicrobial activity. It has been shown to bind directly to FMN riboswitch aptamers (KD = ~100 nM), downregulating the expression of genes responsible for the synthesis and...
Keywords: | 8-Dimethylaminoriboflavin, 8-demethyl-8-(dimethylamino)-riboflavin |
Application: | Flavin mononucleotide (FMN) and riboflavin analog |
CAS | 51093-55-1 |
MW: | 405.4 D |
From 43.00€
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