- Search results for Cay15710
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5 products were found matching "Cay15710"!
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Item number: Cay15710-1
15-keto Prostaglandin F1alpha (15-keto PGF1alpha) is the initial metabolite of PGF1alpha via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and are more active than the parent prostaglandins.Formal...
Keywords: | 15-keto PGF1alpha, 9alpha,11alpha-dihydroxy-15-oxo-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 21562-58-3 |
MW: | 354.5 D |
From 86.00€
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Item number: Cay15777-100
Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-alpha, IL-6,...
Keywords: | AHR 438, NSC 170959, 5-[(3,5-dimethylphenoxy)methyl]-2-oxazolidinone |
Application: | Skeletal muscle relaxant |
CAS | 1665-48-1 |
MW: | 221.3 D |
From 84.00€
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Item number: Cay15557-10
Ramiprilat is the active metabolite of ramipril (Cay-15558) and functions as an angiotensin-converting enzyme inhibitor (pKi = 9.08 in human heart) to suppress the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, thereby preventing vasoconstriction. Furthermore, ramiprilat is reported...
Keywords: | Ramipril Diacid,... |
Application: | ACE inhibitor |
CAS | 87269-97-4 |
MW: | 388.5 D |
From 84.00€
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Item number: Cay15772-10
The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR). CFTR inhibitor II, also known as GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 µM). This compound binds to a site at the external pore of...
Keywords: | Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor II, GlyH-101,... |
Application: | CF transmembrane conductance regulator inhibitor |
CAS | 328541-79-3 |
MW: | 493.2 D |
From 56.00€
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Item number: Cay15775-10
Carmustine is a DNA alkylating agent. It inhibits cell growth and induces cell cycle arrest at the G2/M phase in C6 rat glioma cells when used at a concentration of 10 µM. In vivo, carmustine (0.3 and 6.7 mg/kg per day) reduces tumor growth in a C6 rat glioma model. Carmustine (0.5 mg/kg, i.p.) also reduces the...
Keywords: | bis-Chloroethylnitrosourea, BCNU, Gliadel, NSC 409962, N,N'-bis(2-chloroethyl)-N-nitroso-urea |
Application: | Alkylating agent, DNA replication inhibitor, DNA interstrand crosslinker |
CAS | 154-93-8 |
MW: | 214.1 D |
From 60.00€
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