- Search results for Cay15610
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9 products were found matching "Cay15610"!
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Item number: Cay15610-5
13,14-dihydro Prostaglandin F1alpha (13,14-dihydro PGF1alpha) is a potential metabolite of PGF1alpha. Its biological activity has not been reported. The corresponding compound in the E1 series (13,14-dihydro PGE1) retains biological activity similar to PGE1.Formal Name: 9alpha,11alpha,15S-trihydroxy-prostan-1-oic...
Keywords: | 13,14-dihydro PGF1alpha, PGFalpha, 9alpha,11alpha,15S-trihydroxy-prostan-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 20592-20-5 |
MW: | 358.5 D |
From 86.00€
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Item number: Cay11556-10
N,N-Dimethylamphetamine (N,N-DMA) is a regulated stimulant that is an N-methylated analog of methamphetamine. It is often found as an impurity in preparations of methamphetamine. DMA itself is less active and less neurotoxic than methamphetamine. The metabolites of DMA that are detectable in human urine have been...
Keywords: | Dimetamfetamine, Metrotonin, N,N-Dimethylamphetamine, NSC 27146, NSC 75736, T 312, N,N,alpha-trimethyl-benzeneethanamine,... |
Application: | Analytical reference material, Methamphetamine impurity |
CAS | 33286-27-0 |
MW: | 199.7 D |
From 60.00€
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Item number: Cay15556-100
Paliperidone is an atypical antipsychotic. It is an inverse agonist of dopamine D2 and D3 receptors (IC50s = 1 and 0.9 nM, respectively), as well as an antagonist at these receptors (Kis = 0.4 and 0.1 nM, respectively). Paliperidone also binds to alpha1- and alpha2-adrenergic receptors, histamine H1 receptors, and...
Keywords: | 9-hydroxy Risperidone, RO76477,... |
Application: | Dopamine D2/3-receptor / 5-HT2A-receptor antagonist |
CAS | 144598-75-4 |
MW: | 426.5 D |
From 98.00€
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Item number: Cay15611-10
CGP 37157 is a benzothiazepine that acts as a selective inhibitor of the mitochondrial sodium-calcium exchanger (IC50 = 0.36 µM in isolated mitochondria). It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 is commonly used to study the role...
Keywords: | 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one |
CAS | 75450-34-9 |
MW: | 324.2 D |
From 193.00€
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Item number: Cay15632-10
SN-38 is an inhibitor of topoisomerase I and an active metabolite of the prodrug irinotecan (Cay-14180). It is formed from irinotecan by carboxylesterases. SN-38 (0.1, 1, and 10 µM) induces topoisomerase I-dependent DNA cleavage in a cell-free assay. It induces DNA single-strand breaks in HT-29 colorectal...
Keywords: | 7-ethyl-10-hydroxy-20(S)-Camptothecin, 7-Ethyl-10-Hydroxycamptothecin, NK 012,... |
Application: | Potent DNA topoisomerase I inhibitor |
CAS | 86639-52-3 |
MW: | 392.4 D |
From 66.00€
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Item number: Cay15616-10
Eplerenone is a mineralocorticoid receptor antagonist. It is selective for the mineralocorticoid receptor over glucocorticoid, androgen, progesterone, and estrogen receptors in radioligand binding assays (IC50s = 138, 6,920, 523, >10,000, and 5,702 nM, respectively). Eplerenone inhibits aldosterone-induced...
Keywords: | (+)-Eplerenone, CGP 30083, Epoxymexrenone, SC-6110, SC-66110,... |
Application: | Mineralocorticoid receptor antagonist |
CAS | 107724-20-9 |
MW: | 414.5 D |
From 84.00€
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Item number: Cay15613-10
Cimaterol is a potent agonist of beta-adrenergic receptors (pEC50 = 8.13, 8.78, and 6.62 for human beta1, beta2, and beta3, respectively). Formulations containing cimoterol have been used in farmed animals (swine, fowl, etc.) to increase carcass mass and to alter muscle and fat deposition.Formal Name:...
Keywords: | Cimaterolum, 2-amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-benzonitrile |
Application: | beta1/2/3-adrenergic receptor agonist |
CAS | 54239-37-1 |
MW: | 219.3 D |
From 142.00€
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Item number: Cay15614-50
CyPPA is a positive modulator of the small-conductance calcium-activated potassium channels KCa2.2/SK2 and KCa2.3/SK3 (EC50s = 14 and 5.6 µM, respectively). It is inactive on both KCa2.1/SK1 and the intermediate conductance calcium-activated potassium channel, KCa3.1/SK4. At KCa2.3/SK3, CyPPA increases the apparent...
Keywords: | N-cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methyl-4-pyrimidinamine |
Application: | Small conductance calcium-activated channel SK2/SK3 modulator |
CAS | 73029-73-9 |
MW: | 285.4 D |
From 171.00€
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Item number: Cay15617-50
Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI). It selectively inhibits reuptake of serotonin over norepinephrine reuptake in rat hypothalamic synaptosomes (Kis = 6.2 and 1,100 nM, respectively). Fluvoxamine (10 mg/kg) reduces immobility time in the forced swim test in mice, an effect that can be...
Keywords: | Fevarin, Floxyfral, Luvox(R), MK-264, NSC 309469, (1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone... |
Application: | Selective serotonin reuptake inhibitor |
CAS | 61718-82-9 |
MW: | 434.4 D |
From 43.00€
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