- Search results for Cay15510
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14 products were found matching "Cay15510"!
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Item number: Cay15510-5
11-deoxy Prostaglandin F1beta (11-deoxy PGF1beta) is a synthetic analog of PGF1beta. In contrast to PGF2alpha and PGF1alpha, 11-deoxy PGF1beta exhibits vasodepressor and bronchodilator activities in guinea pigs at a dose of 500 µg/kg.Formal Name: 9beta,15S-dihydroxy-prost-13E-en-1-oic acid. CAS Number: 37785-99-2....
Keywords: | 11-deoxy PGF1beta, 9beta,11-deoxy PGF1alpha, 9beta,15S-dihydroxy-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 37785-99-2 |
MW: | 340.5 D |
From 66.00€
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Item number: Cay15555-10
Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA) as it carries the recognition and phosphorylation site of PKA. Various cultured cells can catalyze the phosphorylation of kemptide in the presence of extracellular ATP and cAMP (Kms = 3-4 µM) with plasma...
Keywords: | NSC 332190 |
Application: | PKA substrate |
CAS | 65189-71-1 |
MW: | 771.9 D |
From 60.00€
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Item number: Cay11155-10
Bromodomains recognize acetylated lysine residues and recruit regulatory complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. The isolated individual or tandem bromodomains of bromodomain-containing protein (BRD) 2 and BRD4 bind acetylated histone tails, which couples...
Keywords: | PF-06405761, 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide |
Application: | Bromodomain inhibitor |
CAS | 1403764-72-6 |
MW: | 347.4 D |
From 52.00€
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Lipid-based Drug Delivery Tools
Item number: Cay15100-1
1,2-Distearoyl-sn-glycero-3-PC (1,2-DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. The transition temperature of 1,2-DSPC is approximately...
Keywords: | 1,2-Distearoyl-sn-glycero-3-Phosphocholine, 1,2-DSPC, Coatsome MC 8080, 1,2-distearoyl-sn-glycero-3-phosphatidylcholine |
Application: | Phospholipid |
CAS | 816-94-4 |
MW: | 790.2 D |
From 69.00€
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Item number: Cay11115-100
Rabbit Anti-S tag IgG conjugated to DyLight(R) 488 Antibody: Anti-S-tag (KETAAAKFERQHMDS) IgG Isotype: IgG Dye: DyLight(R) 488 Excitation max. lambda: 493 nm Emission max. lambda: 518 nm Uses: Flow cytometry, fluorescence-activated cell sorting, and microscopyEmission: 518 nm. Excitation: 493 nm. Formulation:...
Keywords: | Anti-S-tag (KETAAAKFERQHMDS) |
Application: | Fusion protein detection |
Host: | Rabbit |
549.00€
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Lipid-based Drug Delivery Tools
Item number: Cay15110-500
1,2-Dioleoyl-3-trimethylammoniumpropane (DOTAP) is a cationic liposome-forming compound used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. It has been used in the composition of small unilamellar liposomes formulated as a gene delivery vectors for gene therapy.Formal...
Keywords: | DOTAP, 1,2-dioleoyl-3-trimethylammoniumpropane, monochloride |
Application: | Gene delivery, transfection |
CAS | 132172-61-3 |
MW: | 698.5 D |
From 98.00€
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Item number: Cay11510-500
Prostaglandin Bx (PGBx) is a mixture of oligomers of PGB1 with a molecular weight of 1,000-1,500. It has antioxidant and free radical trapping activity that was first studied in isolated mitochondria. PGBx has anti-inflammatory and cytoprotective activity which may be attributed to inhibition of the 14 kDa sPLA2. At...
Keywords: | PGBx |
Application: | Bioactive lipid assays |
CAS | 39306-29-1 |
MW: | 1 D |
From 42.00€
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Item number: Cay15584-10
Formoterol is a selective agonist of the beta2-adrenergic receptor (beta2-AR, Kis = 7.58 and 2,630 nM for beta2- and beta1-ARs, respectively). It is selective for beta-ARs in isolated guinea pig trachea over those in atrial tissue (pD2s = 9.29 and 6.98, respectively) and has a long duration of action. Aerosolized...
Keywords: | rel-N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-formamide,... |
Application: | beta2-adrenergic receptor agonist |
MW: | 402.5 D |
From 130.00€
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Item number: Cay15533-10
JWH 018 (Cay-10900) is a synthetic cannabinoid consisting of an aminoalkylindole moiety and a naphthoyl group. EG 018 is an analog of JWH 018 that has a benzene ring attached to the aminoalkylindole group, positioned adjacent to the naphthoyl group. The physiological and toxicological properties of this compound...
Keywords: | 1-naphthalenyl(9-pentyl-9H-carbazol-3-yl)-methanone |
Application: | Analytical reference standard, Synthetic cannabinoid JWH 018 analog |
CAS | 2219320-91-7 |
MW: | 391.5 D |
From 109.00€
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Item number: Cay15553-10
ON-01910 is a potent, non-ATP-competitive inhibitor of polo-like kinase 1 (Plk1, IC50 = 9 nM), a serine/threonine protein kinase involved in the regulation of cell cycling. It induces apoptosis in a wide array of tumor cell lines (GI50 = 50-200 nM) and blocks the growth of multidrug resistant cancer cell lines....
Keywords: | Rigosertib, N-[2-methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]-glycine, monosodium salt |
Application: | Plk1 inhibitor |
CAS | 1225497-78-8 |
MW: | 473.5 D |
From 46.00€
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Item number: Cay15567-10
Neoruscogenin is a natural sapogenin isolated from Butcher's broom (R. rhizoma), which is traditionally used against chronic venous disorders. It is a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORalpha (EC50 = 110 nM). In mice, neoruscogenin up-regulates the expression of several...
Keywords: | 25(27)-Dehydroruscogenin, spirosta-5,25(27)-diene-1beta,3beta-diol |
Application: | RORalpha agonist |
CAS | 17676-33-4 |
MW: | 428.6 D |
From 161.00€
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Item number: Cay15573-10
Inactivation of the tumor suppressor p53 commonly coincides with increased signaling through NF-kappaB in cancer. CAY10681 is a dual modulator of p53-MDM2 interaction and NF-kappaB signaling. It potently binds MDM2 (Ki = 250 nM), reducing MDM2-mediated turnover of p53. CAY10681 also inhibits phosphorylation of...
Keywords: | 4-(4-bromophenyl)-4,5-dihydro-5-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-1-(phenylmethyl)-pyrrolo[3,4-c]pyrazol-6(1H)-one |
Application: | p53-MDM2 interaction / NF-kappaB signaling modulator |
CAS | 1542066-69-2 |
MW: | 552.5 D |
From 98.00€
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