- Search results for Cay15450
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11 products were found matching "Cay15450"!
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Item number: Cay15450-500
11beta-PGF1beta is the stereoisomer of PGF1alpha with both C-9 and C-11 hydroxyls inverted. There are no published reports on the biological activity of this compound. 11beta-PGF1beta is the stereoisomer of PGF1alpha with both C-9 and C-11 hydroxyls inverted.Formal Name:...
Keywords: | 11-epi PGF1beta, 11beta-PGF1beta, 9beta,11beta-PGF1alpha, 9beta,11beta,15S-trihydroxy-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 37785-86-7 |
MW: | 356.5 D |
From 77.00€
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Item number: Cay15444-500
JWH 019 (Cay-13633) is a cannabimimetic aminoalkylindole that shows a high-affinity for both the central cannabinoid (CB1) and the peripheral cannabinoid (CB2) receptors. JWH 019 N-(4-fluorohexyl) isomer is an isomer of JWH 019 that has a fluorine atom at the four position of the alkyl chain. The physiological and...
Keywords: | JWH 019 N-(4-fluorohexyl) analog, [1-(4-fluorohexyl)-1H-indol-3-yl]-1-naphthalenyl-methanone |
Application: | Analytical reference standard, Cannabimimetic indole JWH 019 derivative |
CAS | 2365471-36-7 |
MW: | 373.5 D |
From 235.00€
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Item number: Cay15418-50
Carvedilol is an antagonist of the beta-adrenergic receptor (beta-AR, Kds = 1.78, 0.4, and 5.01 nM for beta1-, beta2-, and beta3-ARs, respectively). It also selectively binds to alpha1- over alpha2-ARs (Kis = 0.81 and 3,400 nM, respectively). Carvedilol reverses increases in heart rate induced by the beta1-AR...
Keywords: | BM 14190, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol |
Application: | alpha1 / beta adrenergic receptor antagonist |
CAS | 72956-09-3 |
MW: | 406.5 D |
From 43.00€
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Item number: Cay15417-50
Modafinil (Cay-15417) is an analytical reference standard that is classified as a nootropic. It is a wake-promoting agent that binds competitively and selectively to the dopamine transporter, modulating catecholaminergic signaling by inhibiting its activity (IC50 = 3 µM, Ki = 2 µM). With much weaker potency,...
Keywords: | (±)-Modafinil, CEP-1538, CRL 40476, 2-[(diphenylmethyl)sulfinyl]-acetamide |
Application: | Analytical reference standard, Nootropic, Wake-promoting dopamine transporter inhibitor |
CAS | 68693-11-8 |
MW: | 273.4 D |
From 241.00€
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Item number: Cay15433-50
UWA-101 (hydrochloride) (Cay-15433) is an analytical reference material that is structurally categorized as an amphetamine. It inhibits both serotonin and dopamine reuptake (Kis = 467 and 894 nM, respectively), but has no effect on the reuptake of noradrenaline (Ki > 50,000 nM). UWA-101 enhances L-DOPA...
Keywords: | alpha-cyclopropyl-N-methyl-1,3-benzodioxole-5-ethanamine, monohydrochloride |
Application: | Analytical reference material, Amphetamine |
CAS | 1431520-52-3 |
MW: | 255.7 D |
From 109.00€
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Item number: Cay15454-10
A wide variety of aminoalkylindole analogs are potent synthetic cannabinoids (CBs), including many of the JWH compounds. An alkyl chain of five carbons in length produces compounds with high affinity for both the central CB1 and the peripheral CB2 receptors. The addition of a terminal fluorine to the pentyl chain...
Keywords: | 1-(5-fluoropentyl)-1H-indole |
Application: | Analytical reference standard, synthetic cannabinoid base structure |
CAS | 1859218-30-6 |
MW: | 205.3 D |
From 84.00€
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Item number: Cay15427-50
Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM). In vivo, apixaban has antithrombotic effects in a rabbit model of venous thrombosis. Apixaban (357.5 mg) also prevents thrombus formation without inducing adverse bleeding events in a porcine model...
Keywords: | BMS 562247-01,... |
Application: | Factor Xa inhibitor |
CAS | 503612-47-3 |
MW: | 459.5 D |
From 66.00€
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Item number: Cay15414-50
Pitavastatin is an HMG-CoA reductase inhibitor (Ki = 1.7 nM for the rat liver microsomal enzyme). It inhibits sterol biosynthesis in rat liver and ileum (ED50s = 0.13 and 0.2 mg/kg, respectively) and reduces plasma levels of triglycerides and total cholesterol in dogs. Pitavastatin (0.3 mg/kg) increases survival in...
Keywords: | Itabastatin, Itavastatin, NK 104, (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic... |
Application: | HMG-CoA reductase inhibitor |
CAS | 147526-32-7 |
MW: | 440.5 D |
From 84.00€
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Item number: Cay15421-50
Nobiletin is a polymethoxylated flavonoid that has been found in C. unshiu and has diverse biological activities. It reduces LPS- and IFN-gamma-induced increases in inducible nitric oxide synthase (iNOS) protein levels and NO production in RAW 264.7 cells when used at concentrations of 25, 50, and 100 µM. Nobiletin...
Keywords: | NSC 618903, NSC 76751, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one |
Application: | Natural polymethoxylated flavonoid |
CAS | 478-01-3 |
MW: | 402.4 D |
From 48.00€
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Item number: Cay15416-50
Pinacidil is a cyanoguanidine compound that acts as a potassium channel opener, activating the ATP-modulated potassium channels of guinea pig bladder and heart with Ki values of 104 and 251 nM, respectively. It completely relaxes coronary artery rings preconstricted with serotonin (Cay-14332, IC50 = 1.26 µM)....
Keywords: | N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-guanidine, monohydrate |
Application: | Potassium channel opener |
CAS | 85371-64-8 |
MW: | 263.4 D |
From 39.00€
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Item number: Cay15403-50
CAY10683 is a potent histone deacetylase (HDAC) inhibitor isolated from the cyanobacterium Symploca. It inhibits HDAC2 and HDAC6 with IC50 values of 0.119 and 434 nM, respectively, and is without effect against HDAC4 (IC50 = >1,000 nM). CAY10683 inhibits the growth of HCT116 colon cancer cells and HuT-78 cutaneous T...
Keywords: | Santacruzamate A, N-[4-oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid, ethyl ester |
Application: | HDAC inhibitor |
CAS | 1477949-42-0 |
MW: | 278.4 D |
From 64.00€
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