- Search results for Cay15410
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13 products were found matching "Cay15410"!
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Item number: Cay15410-1
PGF1beta is the C-9 epimer of PGF1alpha. It was shown to enhance respiratory rate in experimental animals when administered intravenously.Formal Name: 9beta,11alpha,15S-trihydroxy-prost-13E-en-1-oic acid. CAS Number: 10164-73-5. Synonyms: 9beta-PGF1alpha, PGF1beta. Molecular Formula: C20H36O5. Formula Weight: 356.5....
Keywords: | 9beta-PGF1alpha, PGF1beta, 9beta,11alpha,15S-trihydroxy-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 10164-73-5 |
MW: | 356.5 D |
From 86.00€
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Item number: Cay15444-100
JWH 019 (Cay-13633) is a cannabimimetic aminoalkylindole that shows a high-affinity for both the central cannabinoid (CB1) and the peripheral cannabinoid (CB2) receptors. JWH 019 N-(4-fluorohexyl) isomer is an isomer of JWH 019 that has a fluorine atom at the four position of the alkyl chain. The physiological and...
Keywords: | JWH 019 N-(4-fluorohexyl) analog, [1-(4-fluorohexyl)-1H-indol-3-yl]-1-naphthalenyl-methanone |
Application: | Analytical reference standard, Cannabimimetic indole JWH 019 derivative |
CAS | 2365471-36-7 |
MW: | 373.5 D |
From 235.00€
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Item number: Cay15544-10
FR180204 is a potent cell-permeable inhibitor of ERK1 and ERK2 (Ki = 310 and 140 nM, respectively). It is much less effective against p38alpha (IC50 = 10 µM) and does not inhibit a range of other serine/threonine or tyrosine kinases. FR180204 blocks ERK-mediated signaling from TGF-beta to AP-1 (IC50 = 3.1 µM). It...
Keywords: | ERK Inhibitor II, 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine |
Application: | Cell-permeable ERK1 / ERK2 inhibitor |
CAS | 865362-74-9 |
MW: | 327.3 D |
From 84.00€
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Item number: Cay15487-10
Lysine-specific demethylase 1 (LSD1) is a protein lysine demethylase that specifically demethylates histone H3 lysine 4 (H3K4), resulting in transcriptional repression. SP-2509 is a reversible inhibitor of LSD1 (IC50 = 13 nM). It has no effect on monoamine oxidases A and B. SP-2509 attenuates the binding of LSD1 to...
Keywords: | HCI-2509, LSD1 Inhibitor VII, 3-(4-morpholinylsulfonyl)-benzoic acid (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide |
Application: | LSD1 inhibitor |
CAS | 1423715-09-6 |
MW: | 437.9 D |
From 43.00€
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Item number: Cay15418-50
Carvedilol is an antagonist of the beta-adrenergic receptor (beta-AR, Kds = 1.78, 0.4, and 5.01 nM for beta1-, beta2-, and beta3-ARs, respectively). It also selectively binds to alpha1- over alpha2-ARs (Kis = 0.81 and 3,400 nM, respectively). Carvedilol reverses increases in heart rate induced by the beta1-AR...
Keywords: | BM 14190, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol |
Application: | alpha1 / beta adrenergic receptor antagonist |
CAS | 72956-09-3 |
MW: | 406.5 D |
From 43.00€
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Item number: Cay15417-10
Modafinil (Cay-15417) is an analytical reference standard that is classified as a nootropic. It is a wake-promoting agent that binds competitively and selectively to the dopamine transporter, modulating catecholaminergic signaling by inhibiting its activity (IC50 = 3 µM, Ki = 2 µM). With much weaker potency,...
Keywords: | (±)-Modafinil, CEP-1538, CRL 40476, 2-[(diphenylmethyl)sulfinyl]-acetamide |
Application: | Analytical reference standard, Nootropic, Wake-promoting dopamine transporter inhibitor |
CAS | 68693-11-8 |
MW: | 273.4 D |
From 241.00€
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Item number: Cay15488-10
AMB (Cay-15488) is an analytical reference standard categorized as a synthetic cannabinoid. This product is intended for research and forensic applications.Formal Name: N-[(1-pentyl-1H-indazol-3-yl)carbonyl]-L-valine, methyl ester. CAS Number: 1890250-13-1. Molecular Formula: C19H27N3O3. Formula Weight: 345.4....
Keywords: | AMB-PINACA, AMP, MMB-PINACA, N-[(1-pentyl-1H-indazol-3-yl)carbonyl]-L-valine, methyl ester |
Application: | Analytical reference standard, synthetic cannabinoid AB-PINACA analog |
CAS | 1890250-13-1 |
MW: | 345.4 D |
From 84.00€
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Item number: Cay15414-10
Pitavastatin is an HMG-CoA reductase inhibitor (Ki = 1.7 nM for the rat liver microsomal enzyme). It inhibits sterol biosynthesis in rat liver and ileum (ED50s = 0.13 and 0.2 mg/kg, respectively) and reduces plasma levels of triglycerides and total cholesterol in dogs. Pitavastatin (0.3 mg/kg) increases survival in...
Keywords: | Itabastatin, Itavastatin, NK 104, (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic... |
Application: | HMG-CoA reductase inhibitor |
CAS | 147526-32-7 |
MW: | 440.5 D |
From 84.00€
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Item number: Cay15403-10
CAY10683 is a potent histone deacetylase (HDAC) inhibitor isolated from the cyanobacterium Symploca. It inhibits HDAC2 and HDAC6 with IC50 values of 0.119 and 434 nM, respectively, and is without effect against HDAC4 (IC50 = >1,000 nM). CAY10683 inhibits the growth of HCT116 colon cancer cells and HuT-78 cutaneous T...
Keywords: | Santacruzamate A, N-[4-oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid, ethyl ester |
Application: | HDAC inhibitor |
CAS | 1477949-42-0 |
MW: | 278.4 D |
From 64.00€
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Item number: Cay15421-10
Nobiletin is a polymethoxylated flavonoid that has been found in C. unshiu and has diverse biological activities. It reduces LPS- and IFN-gamma-induced increases in inducible nitric oxide synthase (iNOS) protein levels and NO production in RAW 264.7 cells when used at concentrations of 25, 50, and 100 µM. Nobiletin...
Keywords: | NSC 618903, NSC 76751, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one |
Application: | Natural polymethoxylated flavonoid |
CAS | 478-01-3 |
MW: | 402.4 D |
From 48.00€
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Item number: Cay15420-10
Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14alpha-demethylation of lanosterol, which consequently leads to the inhibition of ergosterol synthesis in fungal cell membranes. Additionally, miconazole has been shown to induce reactive oxygen species in fungal biofilms, demonstrating a...
Keywords: | NSC 169434, R 14889, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole, mononitrate |
Application: | Sterol 14alpha-demethylase inhibitor, Antifungal imidazole |
CAS | 22832-87-7 |
MW: | 479.1 D |
From 44.00€
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Item number: Cay15411-10
cFMS kinase is the cellular homolog of the v-FMS oncogene product of the Susan McDonough strain of the feline sarcoma virus. It can autophosphorlyate colony-stimulating factor (CSF-1), which promotes the survival, proliferation, and differentiation of mononuclear phagocytes. GW 2580 selectively inhibits cFMS kinase...
Keywords: | 5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine |
Application: | CSF1R kinase inhibitor |
CAS | 870483-87-7 |
MW: | 366.4 D |
From 50.00€
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