- Search results for Cay15270
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6 products were found matching "Cay15270"!
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Item number: Cay15270-500
6,15-diketo-13,14-dihydro PGF1alpha is a metabolite of PGI2. It was shown to enhance intracellular cAMP and cholesterol catabolism in bovine arterial smooth muscle cells.Formal Name: 6,15-dioxo-9alpha,11alpha-dihydroxy-prostan-1-oic acid. CAS Number: 63983-53-9. Synonyms: 6,15-diketo-13,14-dihydro PGF1alpha....
Keywords: | 6,15-diketo-13,14-dihydro PGF1alpha, 6,15-dioxo-9alpha,11alpha-dihydroxy-prostan-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 63983-53-9 |
MW: | 370.5 D |
From 43.00€
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Item number: Cay15279-10
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. CAL-101 is a cell permeable inhibitor of the PI3K catalytic subunit p110delta (IC50 = 2.5 nM) that demonstrates 40- to 300-fold selectivity against other PI3K class I enzymes (IC50s = 820, 565, and...
Keywords: | Idelalisib, GS-1101, 5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone |
Application: | Cell permeable PIK3CD inhibitor |
CAS | 870281-82-6 |
MW: | 415.4 D |
From 44.00€
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Item number: Cay15278-50
Clotrimazole is an imidazole antifungal that is active against a wide variety of fungal forms and is effective in many types of fungal infections. It tightly binds sterol 14-alpha demethylase isoform B from A. fumigatus (KD = 103 nM) and, like other imidazoles, disturbs the fungal cell membrane. In mammalian cells,...
Keywords: | BAY-B-5087, NSC 257473, 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole |
Application: | Fungal sterol 14alpha-demethylase inhibitor |
CAS | 23593-75-1 |
MW: | 344.8 D |
From 43.00€
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Item number: Cay15273-10
Aldosterone is a steroid hormone secreted by the adrenal cortex and is the principle mineralocorticoid controlling sodium and potassium balance. Its primary role is to promote unidirectional salt reabsorption in epithelial tissues. Aldosterone is synthesized from cholesterol in the zona glomerulosa of the adrenal...
Keywords: | 18-Aldocorticosterone, NSC 73856, Reichstein X, 11beta,21-dihydroxy-3,20-dioxo-pregn-4-en-18-al |
Application: | Steroid hormone, mineralocorticoid hormone |
CAS | 52-39-1 |
MW: | 360.4 D |
From 43.00€
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Item number: Cay15271-50
2-hydroxy Flutamide is the major metabolite formed during the metabolism of the non-steroidal antiandrogen flutamide by cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4. Through competitive inhibition of the binding of testosterone to the nuclear androgen receptor (AR, IC50 = ~300-900), 2-hydroxy flutamide blocks...
Keywords: | Hydroxyniphtholide, SCH 16423, 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide |
Application: | Antiandrogen, Chemopreventive agent |
CAS | 52806-53-8 |
MW: | 292.2 D |
From 109.00€
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Item number: Cay15272-50
GSK0660 is the first reported antagonist of PPARbeta/delta (IC50 = 155 nM) with no measurable affinity for PPARalpha or PPARgamma (IC50s > 10 µM). Because of the limited bioavailability of GSK0660, the related compound GSK3787 (Cay-15219) was developed as a selective PPARbeta/delta antagonist with more suitable...
Keywords: | 3-[[[2-methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylic acid, methyl ester |
Application: | PPARdelta antagonist |
CAS | 1014691-61-2 |
MW: | 418.5 D |
From 130.00€
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