- Search results for Cay15170
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9 products were found matching "Cay15170"!
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Item number: Cay15170-5
3-methoxy Prostaglandin F1alpha (3-methoxy PGF1alpha) is a novel analog of PGF1alpha with a methoxy group in the 3-position of the upper side chain. There are no published reports describing the pharmacology of 3-methoxy PGF1alpha at this time.Formal Name: 3-methoxy-9alpha,11alpha,15S-trihydroxy-prost-13Z-en-1-oic...
Keywords: | 3-methoxy PGF1alpha, 3-methoxy-9alpha,11alpha,15S-trihydroxy-prost-13Z-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 54432-43-8 |
MW: | 386.5 D |
From 86.00€
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Item number: Cay15177-10
KCNJ1 (Kir1.1, or renal outer medullary potassium channel) and KCNJ13 (Kir7.1) are inwardly rectifying two-transmembrane K+ channels. KCNJ1 has critical roles in kidney function, while KCNJ13 is important in the eye, kidney, and small intestine. VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM) which also...
Keywords: | CID-4536383, ML-111, 7,13-bis(4-nitrobenzyl)-1,4,10-trioxa-7,13-diazacyclopentadecane, dihydrochloride |
Application: | KCNJ1 inhibitor |
CAS | 1783987-83-6 |
MW: | 561.5 D |
From 104.00€
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Item number: Cay15172-10
NADPH oxidase 1 (NOX1) generates reactive oxygen species (ROS) in colon epithelial cells that interacts with both pathogenic and normal bacteria. Excess ROS production, however, is associated with damage to the intestinal mucosa, inflammatory bowel disease, and prostate cancer. ML-090 is the first identified...
Keywords: | CCG-44699, CID-616479, Fluoflavin, NSC 179821, 5,12-dihydro-quinoxalino[2,3-b]quinoxaline |
Application: | NADPH oxidase 1 (NOX-1) inhibitor |
CAS | 531-46-4 |
MW: | 234.3 D |
From 43.00€
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Item number: Cay15175-10
The Ras family of GTPases, including the Arf, Rho, Ras, and Rab GTPase subfamilies, regulates various cellular processes ranging from membrane trafficking to the control of cell proliferation. They regulate cell physiology by switching between active and inactive conformational states by binding either GTP or GDP....
Keywords: | CID-7345532, 1-[2-(2,5-dimethylphenoxy)ethyl]-1H-indole-3-carboxylic acid |
Application: | Rab7 activator |
CAS | 878978-76-8 |
MW: | 309.4 D |
From 60.00€
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Item number: Cay15173-10
Alkaline phosphatases catalyze the hydrolysis of phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. Three isozymes of alkaline phosphatases have been identified in humans, two of which are tissue-specific placental alkaline phosphatase (PLAP), intestinal alkaline...
Keywords: | CID-25067483, 1-(3,4-dihydroxyphenyl)-2-(2-ethyl-1H-imidazol-1-yl)-ethanone, monohydrochloride |
Application: | PLAP inhibitor |
CAS | 1135318-57-8 |
MW: | 282.7 D |
From 60.00€
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Item number: Cay15176-10
ML-099 is a small molecule pan activator of Ras-related GTPases, activating Rac1, cell division cycle 42, Ras, and Rab-2A with EC50 values of 20, 100, 141, and 355 nM, respectively.Formal Name: 2-[(2-phenylethyl)thio]-3-pyridinecarboxylic acid. CAS Number: 496775-95-2. Synonyms: CID-888706. Molecular Formula:...
Keywords: | CID-888706, 2-[(2-phenylethyl)thio]-3-pyridinecarboxylic acid |
Application: | Ras-related GTPase activator |
CAS | 496775-95-2 |
MW: | 259.3 D |
From 50.00€
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Item number: Cay15174-10
ML-097 is a small molecule pan activator of Ras-related GTPases, activating cell division cycle 42, Ras, and Rac1 with EC50 values of 102, 109, and 151 nM, respectively.Formal Name: 2-[(2-bromophenyl)methoxy]-benzoic acid. CAS Number: 743456-83-9. Synonyms: CID-2160985. Molecular Formula: C14H11BrO3. Formula Weight:...
Keywords: | CID-2160985, 2-[(2-bromophenyl)methoxy]-benzoic acid |
Application: | Ras-related GTPase activator |
CAS | 743456-83-9 |
MW: | 307.1 D |
From 60.00€
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Item number: Cay15171-10
Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5,...
Keywords: | CID-2113511, 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-2,5-pyrrolidinedione |
Application: | S1P2 agonist |
CAS | 852230-33-2 |
MW: | 324.4 D |
From 60.00€
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Item number: Cay15179-10
ML-161 is an allosteric, reversible inhibitor of proteinase-activated receptor 1 (PAR1) on platelets, preventing surface expression of P-selectin induced by the peptide SFLLRN with an IC50 value of 0.26 µM. It blocks platelet activation induced by thrombin as well as by SFLLRN but not by PMA (Cay-10008014), U-46619...
Keywords: | AG-670, CID-1048267, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-benzamide |
Application: | PAR1 inhibitor |
CAS | 423735-93-7 |
MW: | 361.2 D |
From 43.00€
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