- Search results for Cay15120-%25
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7 products were found matching "Cay15120-%25"!
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Item number: Cay15160-25
PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM). It has been used as an anticoagulant (100 µM) and to study thrombin-mediated fibrin deposition, angiogenesis, and...
Keywords: | D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone, Pebac,... |
Application: | Thrombin inhibitor |
MW: | 451 D |
From 50.00€
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Item number: Cay15180-25
ML-179 is a potent inverse agonist of liver receptor homolog-1 (LRH-1) (IC50 = 320 nM) with maximum efficacy of 40% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the...
Keywords: | CID-45100448, 3-cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-2,4(1H,3H)-pyrimidinedione |
Application: | NR5A2 inverse agonist |
CAS | 1883548-87-5 |
MW: | 422.4 D |
From 60.00€
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Item number: Cay15140-25
PF-429242 is an inhibitor of site-1 protease with an IC50 value of 170 nM for human recombinant site-1 protease. It is selective for site-1 protease over trypsin, elastase, proteinase K, plasmin, kallikren, factor XIa, thrombin, and furin at concentrations up to 100 µM. PF-429242 completely inhibits proteolytic...
Keywords: | 4-[(diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-benzamide, dihydrochloride |
Application: | MBTPS1 inhibitor, antiviral |
CAS | 2248666-66-0 |
MW: | 482.5 D |
From 68.00€
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Item number: Cay15190-25
The sphingosine 1-phosphate (S1P) receptor S1P3 has roles in vasodilation, epithelial barrier function, cardioprotection, fibrosis, immunity, and inflammation. CYM 5541 is a selective, allosteric agonist of S1P3 (EC50 = 72-132 nM). It less effectively activates S1P1 (EC50 = 28-38 µM) and is ineffective at S1P2,...
Keywords: | CID-17253208, ML-249, N,N-dicyclohexyl-5-cyclopropyl-3-isoxazolecarboxamide |
Application: | Allosteric agonist of S1P3 |
CAS | 945128-26-7 |
MW: | 316.4 D |
From 84.00€
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Item number: Cay17150-25
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
Keywords: | 5-L-isoleucine-angiotensin II, acetate |
Application: | Peptide hormone |
CAS | 68521-88-0 |
MW: | 1046.2 D |
From 34.00€
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Item number: Cay16150-25
1-(1-Naphthyl)piperazine (1-NP) is a ligand for serotonin (5-hydroxytryptamine, 5-HT) receptors. It acts as an antagonist for 5-HT at 5-HT1 and 5-HT2 in rat cortical membranes with IC50 values of 6 and 1 nM, respectively. 1-NP also blocks contraction in the rat fundus induced by either 5-HT or tryptamine (IC50 = 1...
Keywords: | 1-NP, 1-(1-naphthalenyl)-piperazine, monohydrochloride |
Application: | 5-HT1 serotonin receptor agonist, 5-HT2 serotonin receptor antagonist |
CAS | 104113-71-5 |
MW: | 248.7 D |
From 98.00€
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Item number: Cay19150-25
SKF 38393 is a partial agonist of the dopamine D1-like receptors D1 and D5 (Kis = 1 and ~0.5 nM, respectively). It less potently binds D2, D3, and D4 receptors (Kis = ~150, 5,000, and 1,000 nM, respectively).Formal Name: 2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol, monohydrobromide. CAS Number: 20012-10-6....
Keywords: | 2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol, monohydrobromide |
Application: | D1 / D5 dopamine receptor selective partial agonist |
CAS | 20012-10-6 |
MW: | 336.2 D |
From 48.00€
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