- Search results for Cay14995
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11 products were found matching "Cay14995"!
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Item number: Cay14995-50
17-trans Prostaglandin E3 (17-trans PGE3) is an isomer of PGE3 which could theoretically result from the COX metabolism of dietary trans-fatty acids. There are no published reports on the biological activity of this compound.Formal Name: 11alpha,15S-dihydroxy-9-oxo-prosta-5Z,13E,17E-trien-1-oic acid. CAS Number:...
Keywords: | 17-trans PGE3, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E,17E-trien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 210979-33-2 |
MW: | 350.5 D |
From 115.00€
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Item number: Cay14999-5
Ondansetron (hydrochloride hydrate) (Cay-14999) is an analytical reference material categorized as an antiemetic. Formulations containing ondansetron have been used to reduce alcohol consumption and mood disturbances in early-onset alcoholics. This product is intended for research and forensic applications.Formal...
Keywords: | 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate |
Application: | Analytical reference material, Serotonin 5-HT3 receptor antagonist, Antiemetic |
CAS | 103639-04-9 |
MW: | 365.9 D |
84.00€
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Item number: Cay11499-5
Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM). It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and...
Keywords: | GX15-070, 2-[2-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole, monomethanesulfonate |
Application: | Antagonist of Bcl-2 family members containing four Bcl-2 homology domains |
CAS | 803712-79-0 |
MW: | 413.5 D |
From 84.00€
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Item number: Cay14449-5
Tetrahydroharmine (THH) is a fluorescent indole alkaloid extracted from B. caapi, a woody vine that is used to produce a psychoactive beverage, ayahuasca, which has been ritually ingested for medicoreligious purposes throughout South America since pre-Columbian times. THH inhibits monoamine oxidase (MAO)-A and MAO-B...
Keywords: | Leptaflorine, THH, 2,3,4,9-tetrahydro-7-methoxy-1-methyl-1H-pyrido[3,4-b]indole |
Application: | MAO inhibitor |
CAS | 17019-01-1 |
MW: | 216.3 D |
From 62.00€
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Item number: Cay11495-5
Receptors for VEGF have central roles in vasculogenesis and angiogenesis and thus serve as targets for cancer therapy. Cediranib is a potent inhibitor of VEGF receptor tyrosine kinases, including VEGFR1, 2, and 3 (IC50s = 5, 1, and 3 nM, respectively). It also potently inhibits a variety of other receptor and...
Keywords: | AZD 2171, ZD 2171, 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-quinazoline |
Application: | VEGFR1/2/3 inhibitor |
CAS | 288383-20-0 |
MW: | 450.5 D |
From 119.00€
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Item number: Cay14955-10
HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 µM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC50 = 240 µM).Formal Name:...
Keywords: | C-1, 5-(1-piperazinylsulfonyl)-isoquinoline, dihydrochloride |
Application: | Protein kinase inhbitor |
CAS | 210297-47-5 |
MW: | 350.3 D |
From 85.00€
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Item number: Cay14991-5
Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.Formal Name:...
Keywords: | Caspase-8 Substrate (Fluorogenic), N-Acetyl-Leu-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin,... |
Application: | Fluorogenic Caspase-8 substrate |
CAS | 210345-02-1 |
MW: | 729.7 D |
From 85.00€
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Item number: Cay14992-5
Ac-WEHD-AFC is a fluorogenic substrate that can be cleaved by group I caspases (caspase-1, -4, and -5). Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.Formal Name:...
Keywords: | Caspase-1 Substrate (Fluorogenic), Caspase-5 Substrate (Fluorogenic),... |
Application: | Fluorogenic Caspase-1/4/5 substrate |
MW: | 838.7 D |
From 125.00€
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Item number: Cay14996-5
STA-21 is a natural antibiotic that potently inhibits STAT3 by preventing its dimerization and DNA binding when used at concentrations of 20-30 µM. It blocks the growth and survival of cancer cells that express constitutively active STAT3 (e.g., DU145 cells, IC50 = 12.2 µM). STAT3 inhibitors, including STA-21,...
Keywords: | Ochromycinone, (3S)-3,4-dihydro-8-hydroxy-3-methyl-benz[a]anthracene-1,7,12(2H)-trione |
Application: | STAT3 inhibitor |
CAS | 28882-53-3 |
MW: | 306.3 D |
From 163.00€
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Item number: Cay14993-25
Suc-AAPF-pNA is a chromogenic substrate that can be cleaved by cathepsin G (Km = 1.7 mM), subtilisins, chymotrypsin (Km = 60 µM), chymase (Km = 4 mM), and cyclophilin, but not neutrophil elastase. Release of p-nitroanilide is monitored at 405-410 nm. This substrate can be used for inhibitor screening and kinetic...
Keywords: | Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide,... |
Application: | Chromogenic substrate, Inhibitor screening, Kinetic analyses |
CAS | 70967-97-4 |
MW: | 624.7 D |
From 61.00€
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Item number: Cay14998-25
Paroxetine is a selective serotonin reuptake inhibitor (SSRI, Ki = 0.04 nM). It is selective for the serotonin transporter (SERT) over the dopamine and norepinephrine transporters (Kis = 400 and 90 nM, respectively) as well as the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT2A, the histamine H1 receptor,...
Keywords: | BRL 29060A, (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-piperidine, monohydrochloride |
Application: | Serotonin reuptake inhibitor |
CAS | 78246-49-8 |
MW: | 365.8 D |
From 66.00€
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