- Search results for Cay14950
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17 products were found matching "Cay14950"!
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Item number: Cay14950-50
20-hydroxy Prostaglandin E2 (20-hydroxy PGE2) is a product of cytochrome P450 metabolism of PGE2 (Cay-14010). omega-Oxidation at C-20 followed by beta-oxidation and the loss of up to four carbons from the lower side chain is a prominent metabolic pathway for PGE2. 20-hydroxy PGE2 is the putative first intermediate...
Keywords: | 20-hydroxy PGE2, 9-oxo-11alpha,15S,20-trihydroxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 57930-95-7 |
MW: | 368.5 D |
From 85.00€
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Item number: Cay14499-50
Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from S. griseochromogenes. The structure of the pentahydrate form was determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule. It has since been...
Keywords: | 4-[[(3S)-3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeo... |
Application: | Antibiotic |
CAS | 3513-03-9 |
MW: | 458.9 D |
From 54.00€
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Item number: Cay11499-50
Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM). It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and...
Keywords: | GX15-070, 2-[2-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole, monomethanesulfonate |
Application: | Antagonist of Bcl-2 family members containing four Bcl-2 homology domains |
CAS | 803712-79-0 |
MW: | 413.5 D |
From 84.00€
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Item number: Cay14999-50
Ondansetron (hydrochloride hydrate) (Cay-14999) is an analytical reference material categorized as an antiemetic. Formulations containing ondansetron have been used to reduce alcohol consumption and mood disturbances in early-onset alcoholics. This product is intended for research and forensic applications.Formal...
Keywords: | Emeset, GR 38032F, NSC 665799, SN 307,... |
Application: | Analytical reference material, Serotonin 5-HT3 receptor antagonist, Antiemetic |
CAS | 103639-04-9 |
MW: | 365.9 D |
From 146.00€
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Item number: Cay14449-50
Tetrahydroharmine (THH) is a fluorescent indole alkaloid extracted from B. caapi, a woody vine that is used to produce a psychoactive beverage, ayahuasca, which has been ritually ingested for medicoreligious purposes throughout South America since pre-Columbian times. THH inhibits monoamine oxidase (MAO)-A and MAO-B...
Keywords: | Leptaflorine, THH, 2,3,4,9-tetrahydro-7-methoxy-1-methyl-1H-pyrido[3,4-b]indole |
Application: | MAO inhibitor |
CAS | 17019-01-1 |
MW: | 216.3 D |
From 62.00€
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Item number: Cay14953-50
Glutathione (GSH) ethyl ester is a cell-permeable derivative of GSH (Cay-10007461), a nucleophilic co-substrate to glutathione transferases. It increases mitochondrial GSH levels in C38 and IB3-1 epithelial lung cystic fibrosis cells when used at a concentration of 10 mM. GSH ethyl ester (10 mM) decreases reactive...
Keywords: | GSH ethyl ester, L-gamma-glutamyl-L-cysteinyl-glycine, 3-ethyl ester |
Application: | Cell permeable glutathione transferase co-substrate |
CAS | 92614-59-0 |
MW: | 335.4 D |
From 68.00€
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Item number: Cay14910-50
19(R)-hydroxy Prostaglandin E2 (19(R)-hydroxy PGE2) is found in the semen of primates, including man. It is a potent smooth muscle relaxant and a selective agonist for the EP2 receptor. It has an EC50 value of 200 nM for relaxing cat tracheal rings which express EP2 receptors.Formal Name:...
Keywords: | 19(R)-hydroxy PGE2, 19(R)-OH PGE2, 9-oxo-11alpha,15S,19R-trihydroxy-prosta-5Z,13E-dien-1-oic acid |
Application: | EP2 receptor agonist |
CAS | 64625-54-3 |
MW: | 368.5 D |
From 76.00€
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Item number: Cay14914-50
Ionotropic glutamate receptors can be divided into three groups, depending on whether they are activated by alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), kainate, or N-methyl-D-aspartate (NMDA). NBQX is a water-soluble receptor antagonist which targets both AMPA- and kainate-sensitive glutamate...
Keywords: | 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide, disodium salt |
Application: | AMPA / kainate-sensitive glutamate receptor antagonist |
CAS | 479347-86-9 |
MW: | 380.2 D |
From 149.00€
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Item number: Cay14958-50
BMPO is a cyclic nitrone spin trap that can be used for the detection and characterization of thiyl radicals, hydroxyl radicals, and superoxide anions in vitro or in vivo. The BMPO-superoxide adduct does not rapidly decompose to the hydroxyl adduct in cells (t½ = 23 min). Also, the ESR spectrum of the...
Keywords: | BocMPO, 3,4-dihydro-2-methyl-1,1-dimethylethyl ester-2H-pyrrole-2-carboxylic acid-1-oxide |
Application: | Spin trap |
CAS | 387334-31-8 |
MW: | 199.2 D |
From 161.00€
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Item number: Cay14955-10
HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 µM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC50 = 240 µM).Formal Name:...
Keywords: | C-1, 5-(1-piperazinylsulfonyl)-isoquinoline, dihydrochloride |
Application: | Protein kinase inhbitor |
CAS | 210297-47-5 |
MW: | 350.3 D |
From 85.00€
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Item number: Cay14916-50
Protocatechuic acid (PCA) is a dihydroxybenzoic acid phenolic compound found in many edible and medicinal plants. It is a major metabolite of antioxidant polyphenols found in green tea and demonstrates free radical scavenging capability in a 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity assay (IC50 =...
Keywords: | NSC 16631, PCA, 3,4-dihydroxy-benzoic acid |
Application: | Free radical scavenger |
CAS | 99-50-3 |
MW: | 154.1 D |
From 60.00€
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Item number: Cay14917-50
Rasagiline is an inhibitor of monoamine oxidase B (MAO-B, IC50 = 4.43 nM for rat brain enzyme). It is selective for MAO-B over MAO-A (IC50 = 412 nM for rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 µM. Rasagiline inhibits...
Keywords: | (R)-(+)-Rasagiline, (1R)-2,3-dihydro-N-2-propyn-1-yl-1H-inden-1-amine |
Application: | MAO-B inhibitor |
CAS | 136236-51-6 |
MW: | 171.2 D |
From 44.00€
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