3 products were found matching "Cay14920-%25"!
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Vardenafil (hydrochloride hydrate)
Item number: Cay14930-25
Vardenafil is a potent inhibitor of phosphodiesterase 5 (PDE5, IC50s = 0.2-1.2 nM) and PDE6 (IC50 = 2 nM). It is selective for PDE5 and PDE6 over PDE1 and PDE11 (IC50s = 230 and 130 nM, respectively). Vardenafil (4 mg/kg per day for three weeks) improves erectile function in a rat model of acute arteriogenic...
| Keywords: | 2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one,... |
| Application: | PDE5 inhibitor |
| CAS | 330808-88-3 |
| MW: | 579.1 D |
From 142.00€
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KW 3902
Item number: Cay11940-25
KW 3902 is an antagonist of the adenosine A1 receptor (Ki = 0.19 nM). It displays 890-fold selectivity for A1 receptors over A2A receptors and has no activity at A3 receptors. KW 3902 less potently inhibits human organic anion transporter 1 (OAT1, Ki = 7.82 µM). KW 3902 exhibits renal protective effects during...
| Keywords: | MK-7418, Rolofylline, 8-(hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,9-dihydro-1,3-dipropyl-1H-purine-2,6-dione |
| Application: | Adenosine A1 receptor antagonist |
| CAS | 136199-02-5 |
| MW: | 356.5 D |
From 43.00€
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Meloxicam
Item number: Cay14906-25
Meloxicam is a selective inhibitor of COX-2 (IC50s = 11.8 and 143 µM for COX-2 and COX-1, respectively, in an enzyme activity assay) and a non-steroidal anti-inflammatory drug (NSAID). Meloxicam (0.03%) reduces croton oil-induced increases in TNF-alpha and IL-1beta mRNA levels and increases IL-10 mRNA levels in...
| Keywords: | UH-AC 62XX, 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-1,1-dioxide-2H-1,2-benzothiazine-3-carboxamide |
| Application: | COX-2 inhibitor |
| CAS | 71125-38-7 |
| MW: | 351.4 D |
From 43.00€
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