6 products were found matching "Cay14730"!
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15(S)-15-methyl Prostaglandin E2
Item number: Cay14730-1
15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2. It is a potent gastric antisecretory and antiulcer compound. 15(S)-15-methyl PGE2 binds to human myometrium with twice the affinity of PGE2 and is ten times more potent than PGE1 in contracting uterine smooth muscle.Formal Name:...
| Keywords: | 15(S)-15-methyl PGE2, 9-oxo-11alpha,15S-dihydroxy-15-methyl-prosta-5Z,13E-dien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 35700-27-7 |
| MW: | 366.5 D |
From 115.00€
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Posaconazole
Item number: Cay14737-10
Posaconazole is a broad-spectrum triazole antifungal agent active against various yeasts and molds, including Aspergillus, Candida, Fusarium, and Zygomycetes. Posaconazole inhibits the growth of fungi by inhibiting the lanosterol 14alpha-demethylase enzyme (IC50s = 7-200 nM), which results in a disruption in the...
| Keywords: | POS, SCH 56592,... |
| Application: | Antifungal, Lanosterol 14a-demethylase inhibitor |
| CAS | 171228-49-2 |
| MW: | 700.8 D |
From 82.00€
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NNEI 2'-naphthyl isomer
Item number: Cay14738-10
NNEI (Cay-15001) is a synthetic cannabinoid featuring a naphthalene group joined to an indole carboxamide through the one position. NNEI 2'-naphthyl isomer (Cay-14738) differs from NNEI by having the naphthalene group joined at the two position. The physiological or toxicological properties of this compound have not...
| Keywords: | MN-24 2'-naphthyl isomer, N-2-naphthalenyl-1-pentyl-1H-indole-3-carboxamide |
| Application: | Analytical reference standard, synthetic cannabinoid analog |
| CAS | 1338925-12-4 |
| MW: | 356.5 D |
From 109.00€
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Salubrinal
Item number: Cay14735-10
Salubrinal is a selective phosphatase inhibitor that prevents dephosphorylation of eukaryotic translation initiation factor 2 subunit alpha (eIF2alpha), protecting PC12 cells from endoplasmic reticulum stress-mediated apoptosis (EC50 = 15 µM). It appears to block the action of protein phosphatase 1 (PP1) on...
| Keywords: | (2E)-3-phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide |
| Application: | eIF2alpha dephosphorylation (PP1) inhibitor |
| CAS | 405060-95-9 |
| MW: | 479.8 D |
From 35.00€
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WP1066
Item number: Cay14736-10
WP1066 is a cell-permeable inhibitor of STAT3 that directs dephosphorylation and nuclear export of constitutively phosphorylated STAT3 in U87-MG and U373-MG malignant glioma cells when given at a concentration of 10 µM. It also induces apoptosis in U87-MG (IC50 = 5.6 µM) and U373-MG (IC50 = 3.7 µM) cells. WP1066 is...
| Keywords: | STAT Inhibitor III, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylethyl]-2E-propenamide |
| Application: | STAT3 inhibitor |
| CAS | 857064-38-1 |
| MW: | 356.2 D |
From 43.00€
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DC4 Crosslinker
Item number: Cay14734-10
DC4 crosslinker is a mass spectrometry-cleavable crosslinking reagent (18Å in length) that contains two intrinsic positive charges, which allow cross-linked peptides to fragment into their component peptides by collision-induced dissociation or in-source decay. Initial fragmentation events result in cleavage on...
| Keywords: | 1,4-bis[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]-1,4-diazoniabicyclo[2.2.2]octane, dibromide |
| Application: | MS-cleavable crosslinking reagent |
| CAS | 1374647-94-5 |
| MW: | 640.3 D |
From 85.00€
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