- Search results for Cay14725
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11 products were found matching "Cay14725"!
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Item number: Cay14725-1
15(R)-15-methyl Prostaglandin E2 (15(R)-15-methyl PGE2) is a prodrug for the potent PGE2 (Cay-14010) analog 15(S)-15-methyl PGE2 (Cay-14730). Acid-catalyzed epimerization in the stomach produces the 15(S)-hydroxy compound which is biologically active. Oral administration of 15(R)-15-methyl PGE2 to dogs or rats at...
Keywords: | 15(R)-15-methyl PGE2, Arbaprostil, 9-oxo-11alpha,15R-dihydroxy-15-methyl-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 55028-70-1 |
MW: | 366.5 D |
From 115.00€
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Item number: Cay11472-5
Phenazepam (Cay-9000849) is an anxiolytic and hypnotic sedative. 3-hydroxy Phenazepam is a major metabolite of phenazepam. There are significant differences in the rate of phenazepam metabolism in different species, so that 3-hydroxy phenazepam can be detected shortly after oral administration of the parent compound...
Keywords: | 3-hydroxy BD 98, 3-hydroxy Fenazepam, 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one |
Application: | Analytical reference standard, Major phenazepam metabolite |
CAS | 70030-11-4 |
MW: | 365.6 D |
From 76.00€
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Item number: Cay14720-5
15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 (Cay-14010) formed by 15-hydroxy prostaglandin dehydrogenase (15-PGDH). Unlike PGE2, 15-keto PGE2 does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells (Kis = 2.6 and 15 µM, respectively) or induce adenylate cyclase activity...
Keywords: | 15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 26441-05-4 |
MW: | 350.5 D |
From 88.00€
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Item number: Cay14724-5
Docosapentaenoyl ethanolamide is a long-chain omega-3 fatty acid with a hydroxyethylamide group attached at the alpha chain.Formal Name: N-(2-hydroxyethyl)-7Z,10Z,13Z,16Z,19Z-docosapentaenamide. CAS Number: 351317-23-2. Synonyms: 7(Z),10(Z),13(Z),16(Z),19(Z)-Docosapentaenoyl Ethanolamide. Molecular Formula:...
Keywords: | N-(2-hydroxyethyl)-7Z,10Z,13Z,16Z,19Z-docosapentaenamide |
Application: | Bioactive Lipid Assays |
CAS | 351317-23-2 |
MW: | 373.6 D |
From 66.00€
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Item number: Cay14723-5
4(Z),7(Z),10(Z),13(Z),16(Z)-N-(2-hydroxyethyl)-Docosapentaenamide is a long-chain omega-6 fatty acid with a hydroxyethylamide group attached at the alpha chain.Formal Name: N-(2-hydroxyethyl)-4Z,7Z,10Z,13Z,16Z-docosapentaenamide. CAS Number: 211817-55-9. Molecular Formula: C24H39NO2. Formula Weight: 373.6. Purity:...
Keywords: | N-(2-hydroxyethyl)-4Z,7Z,10Z,13Z,16Z-docosapentaenamide |
Application: | Bioactive Lipid Assays |
CAS | 211817-55-9 |
MW: | 373.6 D |
From 66.00€
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Item number: Cay14727-5
2C-E, known formally as 2,5-dimethoxy-4-ethyl phenethylamine, is a psychoactive compound that is regulated as Schedule I in the United States. 25E-NBOMe is a derivative of 2C-E having an N-(2-methoxybenzyl) addition at the amine. This addition on related phenethylamines increases the affinity and selectivity for the...
Keywords: | 2C-E-NBOMe, 4-ethyl-2,5-dimethoxy-N-[(2-methoxyphenyl)methyl]-benzeneethanamine, monohydrochloride |
Application: | Analytical reference standard, 2C-E derivative |
CAS | 1539266-39-1 |
MW: | 365.9 D |
From 225.00€
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Item number: Cay14759-25
IPA-3 is an allosteric inhibitor of p21-activated kinase 1 (PAK1) activation (IC50 = 2.5 µM) that does not inhibit pre-activated PAK1. It selectively inhibits activation of the group I PAKs, PAK1, PAK2, and PAK3 over the group II PAKs, PAK4, PAK5, and PAK6 at 10 µM. IPA-3 inhibits the severe acute respiratory...
Keywords: | 1,1'-dithiobis-2-naphthalenol |
Application: | PAK1 inhibitor |
CAS | 42521-82-4 |
MW: | 350.5 D |
From 77.00€
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Item number: Cay14715-25
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat, respectively). Additionally, it has been shown to compete with other modes of TRPV1 activation, including protons (IC50s = 92.7 and 294 nM for human and rat, respectively),...
Keywords: | (2E)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide |
Application: | TRPV1 antagonist |
CAS | 545395-94-6 |
MW: | 337.4 D |
From 77.00€
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Item number: Cay14743-25
Costunolide is a sesquiterpene lactone that is found naturally in certain plant extracts and in alternative medicine oils. It reduces growth (EC50 = 3-35 µM) and induces apoptosis in assorted cancer cell lines. Costunolide inhibits the activation of Akt (15 µM) in endometriotic epithelial cells and STAT3 activation...
Keywords: | Costus lactone, Melampolide, NSC 106404, 3aS,4,5,8,9,11aR-hexahydro-6E,10E-dimethyl-3-methylene-cyclodeca[b]furan-2(3H)-one |
Application: | Apoptosis inducer |
CAS | 553-21-9 |
MW: | 232.3 D |
From 39.00€
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Item number: Cay14746-25
Abacavir is a nucleoside analog and an inhibitor of HIV-1 reverse transcriptase (Ki = 2.1 µM for the wild-type enzyme). It inhibits replication of a variety of HIV-1 and HIV-2 strains, including strains resistant to 3'-azido-3'-deoxythymidine (zidovudine, Cay-15492) or 2',3'-dideoxyinosine (didanosine, Cay-23715),...
Keywords: | (1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol, monosulfate |
Application: | HIV type 1 reverse transcriptase inhibitor |
CAS | 216699-07-9 |
MW: | 384.4 D |
From 60.00€
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Item number: Cay14072-5
Porcupine (PORCN) is a membrane bound O-acyltransferase that mediates palmitoylation of Wnt family proteins. This step is required for secretion and biologic activity of Wnt proteins, which have roles in embryonic development and cancer. LGK974 is a potent and specific small molecule inhibitor of PORCN (IC50 = 0.4...
Keywords: | PORCN Inhibitor IV, 2',3-dimethyl-N-[5-(2-pyrazinyl)-2-pyridinyl]-[2,4'-bipyridine]-5-acetamide |
Application: | PORCN inhibitor |
CAS | 1243244-14-5 |
MW: | 396.4 D |
From 50.00€
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