3 products were found matching "Cay14720-%25"!
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SIRT1/2 Inhibitor IV
Item number: Cay14407-25
SIRT1/2 inhibitor IV is a cell-permeable inhibitor of SIRT1 (IC50 = 56 µM) and SIRT2 (IC50 = 59 µM), blocking NAD+-dependent deacetylase activity in a substrate competitive manner. It less effectively inhibits SIRT5 (IC50 >300 µM) and has no effect on class I and II histone deacetylases. By inhibiting SIRT1, SIRT1/2...
| Keywords: | Cambinol, NSC 112546, SIRT1 Inhibitor II, SIRT2 Inhibitor VI,... |
| Application: | SIRT1/2 inhibitor |
| CAS | 14513-15-6 |
| MW: | 360.4 D |
From 43.00€
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IRAK-1/4 Inhibitor
Item number: Cay17540-25
Interleukin-1 receptor-associated kinases (IRAKs) are important mediators in the signal transduction of Toll/IL-1 receptor (TIR) family members. Dysregulation of TIR signaling, typified by increased NF-kappaB activity, results in the development of some cancers and other diseases, making the development of IRAK...
| Keywords: | N-[1-[2-(4-morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitro-benzamide |
| Application: | IRAK1 inhibitor, IRAK4 inhibitor |
| CAS | 509093-47-4 |
| MW: | 395.4 D |
From 43.00€
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HOE 33187
Item number: Cay40147-25
HOE 33187 is a derivative of the fluorescent DNA probe Hoechst 33258 (Cay-16756). It is cytotoxic to L1210 murine skin lymphocytic leukemia cells (IC50 = 480 nM).Formal Name: 6-(4-methyl-1-piperazinyl)-2'-phenyl-2,6'-bibenzimidazole. CAS Number: 23623-08-7. Molecular Formula: C25H24N6. Formula Weight: 408.5. Purity:...
| Keywords: | 6-(4-methyl-1-piperazinyl)-2'-phenyl-2,6'-bibenzimidazole |
| Application: | Hoechst 33258 derivative |
| CAS | 23623-08-7 |
| MW: | 408.5 D |
From 80.00€
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