- Search results for Cay14650
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15 products were found matching "Cay14650"!
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Item number: Cay14650-1
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 (Cay-14010) and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Delta13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2...
Keywords: | 13,14-dihydro-15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prost-5Z-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 363-23-5 |
MW: | 352.5 D |
From 104.00€
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Item number: Cay11466-500
JWH 019 (Cay-13633) is a cannabimimetic indole that shows a high-affinity for both the central cannabinoid (CB1) (Ki = 9.8 nM) and the peripheral cannabinoid (CB2) (Ki = 5.6 nM) receptors. JWH 019 N-(6-hydroxyhexyl) beta-D-Glucuronide is an expected major urinary metabolite of JWH 019, based on the metabolism of...
Keywords: | (2S,3S,4S,5R,6R)-6-((6-(3-(1-naphthoyl)-1H-indol-1-yl)hexyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid |
Application: | Analytical reference standard, Expected major urinary JWH 019 metabolite |
CAS | 1630023-00-5 |
MW: | 547.6 D |
From 342.00€
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Item number: Cay14634-50
Cathepsin C is a lysosomal cysteine protease with broad exopeptidase activity that progressively removes dipeptides from various protein and polypeptides substrates. Aside from its role in post-translational processing, cathepsins may also participate in apoptotic signaling pathways by targeting cytosolic caspases...
Keywords: | H-Gly-Phe-BNA, glycyl-N-2-naphthalenyl-L-phenylalaninamide |
Application: | Cathepsin C substrate |
CAS | 21438-66-4 |
MW: | 347.4 D |
From 77.00€
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Item number: Cay14682-50
D-Luciferin is a chemiluminescent substrate of firefly luciferase. It produces light upon oxidative decarboxylation by luciferase in the presence of ATP. D-luciferin can be employed to assay the expression of the luciferase gene linked to a promoter of interest. Alternatively, D-luciferin and luciferase can be used...
Keywords: | 4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-4S-thiazolecarboxylic acid, monosodium salt |
Application: | Chemiluminescent firefly luciferase substrate |
CAS | 103404-75-7 |
MW: | 302.3 D |
From 50.00€
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Item number: Cay14655-10
JWH 081 (Cay-10579) is a cannabimimetic aminoalkylindole that shows a high-affinity for the central cannabinoid (CB1) receptor with a Ki value of 1.2 nM and ten-fold reduced affinity for the peripheral cannabinoid (CB2) receptor (Ki = 12.4 nM). JWH 081-N-(cyclohexylmethyl) analog (Cay-14655) is a synthetic CB where...
Keywords: | [1-(cyclohexylmethyl)-1H-indol-3-yl](4-methoxy-1-naphthalenyl)-methanone |
Application: | Analytical reference standard, synthetic cannabinoid analog |
CAS | 1373876-34-6 |
MW: | 397.5 D |
From 291.00€
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Item number: Cay14656-50
L-Ascorbic acid is a naturally occurring electron donor and therefore serves as a reducing agent. It is synthesized from glucose in the liver of most mammalian species, excluding humans, non-human primates, or guinea pigs who must obtain it through dietary consumption. In humans, L-Ascorbic acid acts as an electron...
Keywords: | Ascorbate, NSC 218455, NSC 33832, Vitamin C, (R)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one |
CAS | 50-81-7 |
MW: | 176.1 D |
From 43.00€
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Item number: Cay14629-50
Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine, the major phospholipid in eukaryotic cells. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicholine demonstrates protective effects in cerebral ischemia, traumatic brain injury, and...
Keywords: | Cytidine 5'-diphosphocholine, Flussorex, Gerolin, Logan, Neurotron, Sinkron, P'-[2-(trimethylammonio)ethyl] ester-cytidine... |
Application: | Phosphatidylcholine synthesis intermediate, CHPT1 substrate |
CAS | 33818-15-4 |
MW: | 510.3 D |
From 43.00€
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Item number: Cay14615-50
Meclizine is a histamine H1 receptor antagonist (Ki = 250 nM). Pretreatment with meclizine (2.5-30 mg/kg, i.p.) reduces ovalbumin-induced mast cell degranulation, edema, and leukocyte influx in rat lung. Formulations containing meclizine have been used in the treatment of motion sickness and vertigo.Formal Name:...
Keywords: | NSC 28728, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-piperazine, dihydrochloride |
Application: | Histamine receptor H1 antagonist |
CAS | 1104-22-9 |
MW: | 463.9 D |
From 125.00€
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Item number: Cay14600-50
Sumatriptan is an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D (IC50s = 9.3 and 7.3 nM, respectively). It also binds to the 5-HT1F receptor (IC50 = 17.8 nM). It induces vasoconstriction in isolated human middle meningeal arteries (EC50 = 89.9 nM), an effect that can be reduced by the 5-HT1B/1D...
Keywords: | GR 43175C, 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide-butanedioic acid |
Application: | Serotonin 5-HT1B/D receptor agonist |
CAS | 103628-48-4 |
MW: | 413.5 D |
From 43.00€
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Item number: Cay14632-50
Dexrazoxane is an intracellular iron chelator and an inhibitor of topoisomerase IIalpha. Through these activities, dexazoxane is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury. Dexrazoxane has also been shown to act as an antioxidant that scavenges hydroxyl (IC50 = 2.1...
Keywords: | ICRF 187, NSC 169780, Totect(R), Zinecard, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-2,6-piperazinedione |
CAS | 24584-09-6 |
MW: | 268.3 D |
From 43.00€
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Item number: Cay14636-50
Platelet-activating factor (PAF) is an important mediator of cell proliferation, angiogenesis, inflammatory response regulation, vasodilation, superoxide formation, and platelet aggregation. These cellular effects are mediated through its specific G-protein coupled receptor, PAFR. Ginkgolide B, a terpenoid extracted...
Keywords: | BN 52021, BN 52051,... |
Application: | PAFr antagonist |
CAS | 15291-77-7 |
MW: | 424.4 D |
From 43.00€
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Item number: Cay14662-50
Zaltoprofen is a cyclooxygenase (COX) inhibitor that displays slight preferential inhibition for COX-2 (IC50s = 1.3 and 0.34 µM for COX-1 and COX-2, respectively). Independent of COX inhibition, zaltoprofen has also been reported to inhibit bradykinin-induced nociceptive responses by blocking the activation of...
Keywords: | CN 100, Soleton, 10,11-dihydro-a-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid |
Application: | COX inhibitor |
CAS | 74711-43-6 |
MW: | 298.4 D |
From 115.00€
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