17 products were found matching "Cay14510"!

Tunicamycin mixture is a mixture of tunicamycins with variable trans-2,3-unsaturated branched chain fatty acid (BFCA) chain lengths. Tunicamycins are anti-microbial agents that are active against Gram-positive bacteria, fungi, and viruses. They inhibit the N-acetylhexosamine (HexNAc) phosphotransferase family of...

11beta-PGE2 is the C-11 epimer of PGE2. It is a moderate inhibitor of PGE2 binding to rat hypothalamic membranes with a Ki value of 53 nM. 11beta-PGE2 also stimulates bone resorption in rats at concentrations of 10 to 1,000 nM which is similar to PGE2. 11beta-PGE2 inhibits PGE2 binding to the prostaglandin...

Ketanserin is a potent antagonist of the serotonin receptor 5-HT2A (Ki = 3.16 nM) that has hypertensive effects in vivo. RH-34 is a derivative of ketanserin in which the 4-(p-fluorobenzoyl)piperidine group has been replaced with an N-(2-methoxybenzyl) moiety. In phenethylamines, which are 5-HT2A agonists, this...

PB-22 (Cay-14096) is a synthetic cannabinoid that is structurally analogous to the potent aminoalkylindoles like JWH 018 (Cay-10900). It differs from JWH 018 by having 8-hydroxyquinoline replacing the naphthalene group of JWH 018. PB-22 5-hydroxyisoquinoline isomer is a structural isomer of PB-22. The physiological...

Cilostamide is a selective inhibitor of phosphodiesterase (PDE)3A and PDE3B with IC50 values of 27 and 50 nM, respectively. It is less selective for inhibition of PDE1, PDE2, PDE4, PDE5, and PDE7 (IC50s = 12 to > 300 µM). Cilostamide has been shown to inhibit thrombin-induced platelet aggregation with an IC50 value...

Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 µM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value...

BB-22 (Cay-14099) is an analog of the potent synthetic cannabinoid JWH 018 (Cay-10900) that is structurally similar to PB-22 (Cay-14096) and its derivative, 5-fluoro PB-22 (Cay-14095). Both BB-22 and PB-22 are distinctive in that an 8-hydroxyquinoline replaces the naphthalene group of JWH 018. BB-22...

5-fluoro PB-22 (Cay-14095) is a synthetic cannabinoid that is an analog of potent 5-fluoropentyl JWH-type cannabimimetics. 5-fluoro PB-22 3-hydroxyquinoline isomer differs from 5-fluoro PB-22 by having the ester linkage inserted at the three, rather than at the eight, position of the quinoline moiety. The...

PB-22 (Cay-14096) is a synthetic cannabinoid that is structurally analogous to the potent aminoalkylindoles like JWH 018 (Cay-10900). It differs from JWH 018 by having 8-hydroxyquinoline replacing the naphthalene group of JWH 018. PB-22 7-hydroxyquinoline isomer is a structural isomer of PB-22. The physiological and...

BB-22 (Cay-14099) is an analog of the potent synthetic cannabinoid JWH 018 (Cay-10900) that is structurally similar to PB-22 (Cay-14096) and its derivative, 5-fluoro PB-22 (Cay-14095). Both BB-22 and PB-22 are distinctive in that an 8-hydroxyquinoline replaces the naphthalene group of JWH 018. BB-22...

BB-22 (Cay-14099) is an analog of the potent synthetic cannabinoid JWH 018 (Cay-10900) that is structurally similar to PB-22 (Cay-14096) and its derivative, 5-fluoro PB-22 (Cay-14095). Both BB-22 and PB-22 are distinctive in that an 8-hydroxyquinoline replaces the naphthalene group of JWH 018. BB-22...

2C-T is a 2,5-dimethoxy phenethylamine that has structural and pharmacokinetic properties similar to the psychedelic mescaline. 25T-NBOMe is a derivative of 2C-T having an N-(2-methoxybenzyl) addition at the amine. This addition on related phenethylamines increases the affinity and selectivity for the 5-HT2A...