2 products were found matching "Cay14420-%25"!
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Thioridazine (hydrochloride)
Item number: Cay14400-25
Thioridazine is a typical antipsychotic. It binds to dopamine D2, histamine H1, M3 muscarinic, and alpha1- and alpha2-adrenergic receptors (Kis = 5-341.3 nM), as well as the serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = 10-180.7 nM). Thioridazine (5 mg/kg) reduces...
| Keywords: | Aldazine, NSC 186060, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine, monohydrochloride |
| Application: | Dopamine D2-receptor antagonist |
| CAS | 130-61-0 |
| MW: | 407 D |
From 43.00€
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PJ-34 (hydrochloride)
Item number: Cay14440-25
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. PJ-34 is an inhibitor of PARPs which can be used in cells or in animals. It binds and inhibits the PARP tankyrase1 (IC50 = 1 µM). PJ-34 also...
| Keywords: | N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)-acetamide, monohydrochloride |
| Application: | PARP inhibitor |
| CAS | 344458-15-7 |
| MW: | 331.8 D |
From 50.00€
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