7 products were found matching "Cay14420"!
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9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
Item number: Cay14420-10
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 (PGE2, Cay-14010) with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular...
| Keywords: | 9-deoxy-9-methylene-16,16-dimethyl PGE2, Meteneprost,... |
| Application: | Bioactive lipid assays |
| CAS | 61263-35-2 |
| MW: | 378.6 D |
From 69.00€
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Anti-Multiubiquitin Chain (Clone FK2)
Item number: Cay14220-100
Ubiquitin is a small protein composed of 76 amino acids and having a molecular weight of 8.6 kD. It exists in all eukaryotic cells and is responsible for numerous functions in the cell by post-translational modifications of substrate proteins (ubiquitination). This process is important to numerous cellular processes...
| Keywords: | Anti-Mono-Ubiquitinylated conjugates, Anti-Poly-Ubiquitinylated conjugates, Anti-Monoubiquitinylated conjugates,... |
| Application: | ELISA, IHC, WB |
| Host: | Mouse |
| Species reactivity: | human |
261.00€
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Doxycycline (hyclate)
Item number: Cay14422-10
Doxycycline is a broad-spectrum tetracycline antibiotic. It inhibits bacterial protein synthesis by binding to ribosomes. Doxycycline also selectively inhibits human matrix metalloproteinase-8 (MMP-8) and MMP-13 over MMP-1 with 50, 60, and 5% inhibition, respectively, when used at a concentration of 30 µM. It can be...
| Keywords: | (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-... |
| Application: | Antibiotic |
| CAS | 24390-14-5 |
| MW: | 1025.9 D |
From 43.00€
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Cordycepin
Item number: Cay14426-10
Cordycepin is a nucleoside analog originally isolated from C. militaris that has diverse biological activities. Upon entry into cells, it is converted to cordycepin triphosphate, which inhibits ATP-dependent DNA and RNA synthesis. It incorporates into DNA and RNA at internal and terminal positions in SK-HEP-1 cells....
| Keywords: | 3'-Deoxyadenosine, NSC 401022, NSC 63984, 3'-deoxy-adenosine |
| Application: | Nucleoside analog, polyadenylation inhibitor |
| CAS | 73-03-0 |
| MW: | 251.2 D |
From 46.00€
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Melatonin
Item number: Cay14427-10
Melatonin is an indoleamine neurohormone whose levels vary in a daily cycle, thereby allowing the entrainment of the circadian rhythms of several biological functions in animals, plants, and microbes. Many biological effects of melatonin are transduced through melatonin receptors, including the MT1, MT2, and MT3...
| Keywords: | NSC 113928, NSC 56423, Regulin, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-acetamide |
| Application: | Neurohormone, Antioxidant |
| CAS | 73-31-4 |
| MW: | 232.3 D |
From 43.00€
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Darifenacin (hydrobromide)
Item number: Cay14424-10
Darifenacin is an antagonist of M3 muscarinic acetylcholine receptors (mAChRs, Ki = 0.76 nM). It is selective for M3 over M1, M2, M4, and M5 mAChRs (Kis = 7.08, 44.67, 45.71, and 9.33 nM, respectively). Darifenacin selectively inhibits contractions in isolated guinea pig ileum, bladder, and trachea (pA2s = 9.44,...
| Keywords: | UK 88525-04, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-alpha,alpha-diphenyl-3-pyrrolidineacetamide, monohydrobromide |
| Application: | Muscarinic receptor antagonist |
| CAS | 133099-07-7 |
| MW: | 507.5 D |
From 92.00€
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Teniposide
Item number: Cay14425-10
Teniposide is a topoisomerase II poison. It promotes calf thymus topoisomerase II-mediated DNA cleavage when used at concentrations ranging from 0.04 to 40 µg/ml. Teniposide induces single- and double-stranded DNA breaks in a concentration-dependent manner. It inhibits the proliferation of A549 lung cancer cells...
| Keywords: | NSC 122819, VM-26,... |
| Application: | Topoisomerase II inhibitor |
| CAS | 29767-20-2 |
| MW: | 656.7 D |
From 43.00€
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