- Search results for Cay14350
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10 products were found matching "Cay14350"!
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Item number: Cay14350-500
8-iso Prostaglandin E2 (8-iso PGE2) is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 µM, respectively. When infused into the renal...
Keywords: | 8-epi PGE2, 8-iso PGE2, 9-oxo-11alpha,15S-dihydroxy-(8beta)-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 27415-25-4 |
MW: | 352.5 D |
From 76.00€
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Item number: Cay14354-10
XLR11 (Cay-11565) is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB2 receptor over the central CB1 receptor. XLR11 also has an N-(5-fluoropentyl) chain, which increases binding to both CB receptors. XLR11 6-hydroxyindole metabolite is...
Keywords: | 5-fluoro UR-144 6-hydroxyindole metabolite,... |
Application: | Analytical reference standard, Expected minor monohydroxylated urinary XLR11 metabolite |
CAS | 1630022-98-8 |
MW: | 345.5 D |
From 158.00€
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Item number: Cay14321-50
AEBSF is a water soluble, irreversible, broad spectrum inhibitor of serine proteases, including trypsin, chymotrypsin, plasmin, thrombin, and kallikreins. AEBSF can also prevent the activation of the ROS generator, NADPH oxidase. At 10-50 µg, AEBSF can attenuate airway inflammation in a mouse model of airway...
Keywords: | Pefabloc SC, 4-(2-aminoethyl)-benzenesulfonyl fluoride, monohydrochloride |
Application: | Serine protease inhibitor |
CAS | 30827-99-7 |
MW: | 239.7 D |
From 65.00€
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Item number: Cay14330-50
Ponceau S is a stain that permits the rapid, reversible detection of proteins immobilized on various matrices, including nitrocellulose and polyvinylidene fluoride membranes. It can be used to locate proteins or evaluate efficiency of transfer. Reversible staining with ponceau S has also been validated as an...
Keywords: | Acid Red 112, 3-hydroxy-4-[2-[2-sulfo-4-[2-(4-sulfophenyl)diazenyl]phenyl]diazenyl]-2,7-naphthalenedisulfonic acid,... |
Application: | Protein staining |
CAS | 6226-79-5 |
MW: | 760.6 D |
From 50.00€
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Item number: Cay14328-50
Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site. It is used in cell biology as a selective agent in cell culture systems....
Keywords: | (4S,4aS,5aS,6S,12aS)-... |
Application: | Antibiotic |
CAS | 64-75-5 |
MW: | 480.9 D |
From 48.00€
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Item number: Cay14397-50
G protein-coupled estrogen receptor (GPER), or GPR30, specifically binds natural and man-made estrogens. It is thought to be involved in estrogen-sensitive cancers. GPER knockout mice are fertile, although they exhibit thymic atrophy, impaired glucose tolerance, and altered bone growth. G-36 is a cell-permeable...
Keywords: | (4S)-rel-4-(6-bromo-1,3-benzodioxol-5-yl)-3aR,4,5,9bS-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline |
Application: | GPER antagonist |
CAS | 1392487-51-2 |
MW: | 412.3 D |
From 43.00€
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Item number: Cay14307-50
CZC-24832 is an inhibitor of PI3Kgamma (IC50 = 0.025 µM in a binding assay). It is selective for PI3Kgamma over PI3Kdelta, PI3Kalpha, and PI3Kbeta (IC50s = 7.9, >10, and 1.26 µM, respectively, in binding assays), as well as a panel of 154 lipid and protein kinases. CZC-24832 inhibits phosphorylation of Akt induced...
Keywords: | 5-(2-amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-3-pyridinesulfonamide |
Application: | PI3K gamma inhibitor |
CAS | 1159824-67-5 |
MW: | 364.4 D |
From 131.00€
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Item number: Cay14312-50
PU 02 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 with IC50 values ranging from 0.36 to 1.3 µM for human 5-HT3A, 5-HT3AB, 5-HT3AC, and 5-HT3AE in a FLIPR membrane potential assay using HEK293 cells expressing human recombinant receptors. It is selective for 5-HT3 over other Cys-loop containing...
Keywords: | 6-[(1-naphthalenylmethyl)thio]-9H-purine |
Application: | 5-hydroxytryptamine receptor 3A (5-HT3-A) antagonist |
CAS | 313984-77-9 |
MW: | 292.4 D |
From 114.00€
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Item number: Cay14351-10
Yangonin is a natural kavalactone from the kava plant, P. methysticum. It enhances the binding of bicuculline at the gamma-amino butyric acid (GABA) receptor GABAA at 1.0 µM. Yangonin also binds the central cannabinoid (CB1) receptor with a Ki value of 0.72 µM, but whether it serves as an agonist or antagonist at...
Keywords: | 4-methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one |
Application: | CB1 receptor binding |
CAS | 500-62-9 |
MW: | 258.3 D |
From 84.00€
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Item number: Cay14304-50
PNU 120596 is a positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor (nAChR), increasing agonist-evoked calcium flux (EC50 = 216 nM). It has no detectable effect on alpha4beta2, alpha3beta4, or alpha9beta10 nAChRs. PNU-120596 increases the frequency of ACh-evoked GABAergic...
Keywords: | NSC 216666, N-(5-chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea |
Application: | Positive allosteric CHRNA7 modulator |
CAS | 501925-31-1 |
MW: | 311.7 D |
From 66.00€
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