Kahweol is a natural diterpene that is isolated from coffee beans. It increases glutathione S-transferase activity in the gut mucosa of mice and, with the diterpene cafestol, induces glutathione S-transferase expression in rat livers. Kahweol has anti-inflammatory effects in RAW macrophages, inhibiting LPS-induced...

Reversine is a 2,6-disubstituted purine derivative that was originally found to induce dedifferentiation of C2C12 culture myoblast cells into stem cell progenitors when used at a concentration of 5 µM for four days. Depending on cell type, reversine promotes either differentiation or dedifferentiation. For example,...