10 products were found matching "Cay14011"!

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Prostaglandin E2 methyl ester
Prostaglandin E2 methyl ester

Item number: Cay14011-1

Prostaglandin E2 methyl ester (PGE2 methyl ester) is an analog of PGE2 (Cay-14010) with enhanced lipid solubility. PGE2 is one of the primary cyclooxygenase products of arachidonic acid (Cay-90010) and one of the most widely investigated PGs. Its activity influences inflammation, fertility and parturition, gastric...
Keywords: Dinoprostone methyl ester, PGE2 methyl ester, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, methyl ester
Application: Bioactive lipid assays
CAS 31753-17-0
MW: 366.5 D
From 43.00€ *
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Thioridazine (hydrochloride)
Thioridazine (hydrochloride)

Item number: Cay14400-1

Thioridazine is a typical antipsychotic. It binds to dopamine D2, histamine H1, M3 muscarinic, and alpha1- and alpha2-adrenergic receptors (Kis = 5-341.3 nM), as well as the serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = 10-180.7 nM). Thioridazine (5 mg/kg) reduces...
Keywords: Aldazine, NSC 186060, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine, monohydrochloride
Application: Dopamine D2-receptor antagonist
CAS 130-61-0
MW: 407 D
From 43.00€ *
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PJ-34 (hydrochloride)
PJ-34 (hydrochloride)

Item number: Cay14440-1

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. PJ-34 is an inhibitor of PARPs which can be used in cells or in animals. It binds and inhibits the PARP tankyrase1 (IC50 = 1 µM). PJ-34 also...
Keywords: N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)-acetamide, monohydrochloride
Application: PARP inhibitor
CAS 344458-15-7
MW: 331.8 D
From 50.00€ *
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CAY10657
CAY10657

Item number: Cay11140-1

The NF-kappaB/Rel family of transcription factors induce and coordinate the expression of pro-inflammatory genes including cytokines, chemokines, interferons, MHC proteins, growth factors, and cell adhesion molecules. Under resting conditions NF-kappaB dimers are retained in the cytoplasm by a member of the IkappaB...
Keywords: 3-[(aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide
Application: Potential IKK-2 inhibitor
CAS 494772-86-0
MW: 360.4 D
From 58.00€ *
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(1R,3S)-3-Aminocyclopentane carboxylic acid
(1R,3S)-3-Aminocyclopentane carboxylic acid

Item number: Cay11401-50

(1R,3S)-3-Aminocyclopentane carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: (1R,3S)-3-amino-cyclopentanecarboxylic acid. CAS Number: 71830-08-5. Molecular Formula: C6H11NO2. Formula Weight: 129.2. Purity: >95%. Formulation: (Request formulation change), A neat oil....
Keywords: (1R,3S)-3-amino-cyclopentanecarboxylic acid
Application: Synthetic intermediate
CAS 71830-08-5
MW: 129.2 D
114.00€ *
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(±)-Alliin
(±)-Alliin

Item number: Cay14001-50

Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor. Alliin exhibits anti-cancer, anti-microbial, anti-hypertensive, cardioprotective, and anti-oxidant activities. It has been shown to inhibit squalene monooxygenase, a...
Keywords: (±)-Allyl-L-cysteine sulfoxide, S-2-propen-1-yl-S-oxide-L-cysteine
Application: Metabolic studies
CAS 17795-26-5
MW: 177.2 D
From 114.00€ *
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Prostaglandin E2
Prostaglandin E2

Item number: Cay14010-1

PGE2 is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors...
Keywords: Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 363-24-6
MW: 352.5 D
From 35.00€ *
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Prostaglandin E2 Ethanolamide
Prostaglandin E2 Ethanolamide

Item number: Cay14012-1

Prostaglandin E2 ethanolamide (PGE2-EA) is an analog of PGE2 (Cay-14010) with improved water solubility and stability. PGE2-EA is formed via COX-2 metabolism of arachidonoyl ethanolamide (AEA, Cay-90050) and acts as an agonist at E prostanoid (EP) receptors 1-4 (Kis = 2.45, 0.46, 0.2, and 0.51 µM, respectively). It...
Keywords: Dinoprostone Ethanolamide, PGE2-EA, Prostamide E2, N-(2-hydroxyethyl)-9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-amide
Application: EP receptor agonist
CAS 194935-38-1
MW: 395.5 D
From 44.00€ *
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Iberin
Iberin

Item number: Cay14016-1

Iberin is a natural isothiocyanate found in cruciferous plants. When introduced into the daily diet of rats or added to rat hepatocytes (40 µM), it induces the expression of phase II detoxification enzymes, including quinone reductase and glutathione S-transferase. In addition, iberin activates the nuclear factor...
Keywords: NSC 321801, 1-isothiocyanato-3-(methylsulfinyl)-propane
Application: Natural isothiocyanate
CAS 505-44-2
MW: 163.3 D
From 43.00€ *
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5-Methoxyindole-3-acetic Acid
5-Methoxyindole-3-acetic Acid

Item number: Cay14019-1

5-Methoxyindole-3-acetic acid (5-MIAA) is a methoxyindole that is synthesized in rat pineal gland, retina, and harderian gland. Following conversion to a peroxyl radical by horseradish peroxidase (HRP), 5-MIAA increases the rate of formation of thiobarbituric acid reactive substances (TBARS) in liposomes and is...
Keywords: 5-Methoxy-IAA, 5-Methoxyindoleacetic acid, 5-MIAA, 5-methoxy-1H-indole-3-acetic acid
Application: Pineal indolamine
CAS 3471-31-6
MW: 205.2 D
From 54.00€ *
Review