- Search results for Cay14010
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6 products were found matching "Cay14010"!
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Item number: Cay14010-5
PGE2 is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors...
Keywords: | Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 363-24-6 |
MW: | 352.5 D |
From 35.00€
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Item number: Cay11440-10
Gram negative bacteria utilize N-acylated homoserine lactones to coordinate expression of virulence in response to the density of the surrounding bacterial population in a process termed quorum sensing. By interfering with this communication and thereby disrupting virulence expression, quorum sensing inhibitors are...
Keywords: | NSC 402844, 3-methoxy-5-methyl-4-oxo-2,5-hexadienoic acid |
Application: | Antibiotic |
CAS | 90-65-3 |
MW: | 170.2 D |
From 66.00€
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Item number: Cay14000-10
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis....
Keywords: | 7-Geranyloxycoumarin, 7-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-2H-1-benzopyran-2-one |
Application: | Metabolic studies |
CAS | 495-02-3 |
MW: | 298.4 D |
From 39.00€
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Item number: Cay14400-10
Thioridazine is a typical antipsychotic. It binds to dopamine D2, histamine H1, M3 muscarinic, and alpha1- and alpha2-adrenergic receptors (Kis = 5-341.3 nM), as well as the serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = 10-180.7 nM). Thioridazine (5 mg/kg) reduces...
Keywords: | Aldazine, NSC 186060, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine, monohydrochloride |
Application: | Dopamine D2-receptor antagonist |
CAS | 130-61-0 |
MW: | 407 D |
From 43.00€
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Item number: Cay11140-10
The NF-kappaB/Rel family of transcription factors induce and coordinate the expression of pro-inflammatory genes including cytokines, chemokines, interferons, MHC proteins, growth factors, and cell adhesion molecules. Under resting conditions NF-kappaB dimers are retained in the cytoplasm by a member of the IkappaB...
Keywords: | 3-[(aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide |
Application: | Potential IKK-2 inhibitor |
CAS | 494772-86-0 |
MW: | 360.4 D |
From 58.00€
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Item number: Cay14440-10
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. PJ-34 is an inhibitor of PARPs which can be used in cells or in animals. It binds and inhibits the PARP tankyrase1 (IC50 = 1 µM). PJ-34 also...
Keywords: | N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)-acetamide, monohydrochloride |
Application: | PARP inhibitor |
CAS | 344458-15-7 |
MW: | 331.8 D |
From 50.00€
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