- Search results for Cay13825
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12 products were found matching "Cay13825"!
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Item number: Cay13825-500
Misoprostol is a widely sold analog of prostaglandin E1 (PGE1) which has potent but relatively non-selective agonist activity with respect to the prostanoid EP receptor subgroup. Misoprostol has been used therapeutically for many years in humans for the treatment of gastric ulcer disease under the Searle tradename...
Keywords: | 9-oxo-11beta,16-dihydroxy-16-methyl-prost-13E-en-1-oic acid, methyl ester |
Application: | Bioactive lipid assays |
CAS | 58717-36-5 |
MW: | 382.5 D |
From 236.00€
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Item number: Cay13382-5
DAz-2 is a cell-permeable chemical probe used to detect cysteine oxidation in proteins. Redox-sensitive cysteine residues in proteins may function as sensors of reactive oxygen species (ROS) and also serve as molecular switches, activating or deactivating proteins, following a change in oxidation state. Modification...
Keywords: | Click Tag(TM) DAz-2, DCP-N3, 4-(3-azidopropyl)cyclohexane-1,3-dione |
Application: | Sulfenic acid probe |
CAS | 1176905-54-6 |
MW: | 195.2 D |
From 84.00€
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Item number: Cay13338-25
The Src family of proto-oncogenic kinases include nine mammalian non-receptor tyrosine kinases that are involved in intracellular signaling and are often relevant to carcinogenesis. SU6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). It weakly...
Keywords: | 2,3-dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
Application: | Src kinase inhibitor |
CAS | 330161-87-0 |
MW: | 371.5 D |
From 32.00€
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Item number: Cay13828-5
3-Deazaneplanocin A is a cyclopentenyl analog of 3-deazaadenosine, originally synthesized as an inhibitor of S-adenosyl-L-homocysteine hydrolase. It has been shown to deplete EZH2 levels and to inhibit trimethylation of lysine 27 on histone H3 in cultured human acute myeloid leukemia (AML) HL-60 and OCI-AML3 cells...
Keywords: | DZNep, NSC 617989, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol |
Application: | S-adenosyl-L-homosysteine hydrolase inhibitor |
CAS | 102052-95-9 |
MW: | 262.3 D |
From 130.00€
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Item number: Cay13820-5
Misoprostol is an analog of prostaglandin E1 (PGE1, Cay-13010) and an agonist of the PGE2 receptor subtypes EP2 and EP3. It binds to EP1, EP2, EP3-III, and EP4 receptors (Kis = 35.675, 10.249, 0.319, 5.499 µM, respectively) and is selective for EP receptors over DP, FP, IP, and TP receptors (Kis = >100 µM for all)....
Keywords: | SC 29333, 9-oxo-11alpha,16-dihydroxy-16-methyl-prost-13E-en-1-oic acid, methyl ester |
Application: | EP receptor agonist |
CAS | 59122-46-2 |
MW: | 382.5 D |
From 27.00€
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Item number: Cay13821-5
Misoprostol is a prostaglandin E1 (Cay-13010) analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 µg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 µM), and relax fetal rabbit ductus arteriosus...
Keywords: | 9-oxo-11alpha,16-dihydroxy-16-methyl-prost-13E-en-1-oic acid |
Application: | EP receptor agonist |
CAS | 112137-89-0 |
MW: | 368.5 D |
From 76.00€
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Item number: Cay13823-5
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes. AX 048 is a potent group IVA cPLA2 inhibitor that demonstrates 50%...
Keywords: | 4-[(1,2-dioxohexadecyl)amino]-butanoic acid, ethyl ester |
Application: | cPLA2 inhibitor |
CAS | 873079-69-7 |
MW: | 383.6 D |
From 189.00€
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Item number: Cay13835-25
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Cay-90310). It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines. RvD4, at 10 ng/mouse, reduces neutrophil...
Keywords: | RvD4, (4S,5R,6E,8E,10Z,13Z,15E,17S,19Z)-4,5,17-trihydroxy-6,8,10,13,15,19-docosahexaenoic acid |
CAS | 1025684-60-9 |
MW: | 376.5 D |
From 205.00€
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Item number: Cay13861-25
Fmoc-Succinimide (Fmoc-OSu) is a mixed carbamate reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxyamino acids and hydroxyamino acid esters in high yields. Fmoc-OSu is a more preferable alternative to the use of the chloroformate, Fmoc-Cl, because it eliminates the...
Keywords: | FMOC-OSu, N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 2,5-dioxo-1-pyrrolidinyl 9H-fluoren-9-ylmethyl ester-carbonic acid |
Application: | Chemical synthesis |
CAS | 82911-69-1 |
MW: | 337.3 D |
From 43.00€
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Item number: Cay13838-25
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3, important second messengers that modulate the activity of downstream targets Akt and mTOR. Aberrant PI3K/Akt is associated with many human cancers. CAY10626 is a...
Keywords: | N-[2-(dimethylamino)ethyl]-N-methyl-4-[[[[4-[4-(4-morpholinyl)-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]ph... |
Application: | PI3K inhibitor |
CAS | 1202884-94-3 |
MW: | 624.7 D |
From 141.00€
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Item number: Cay13891-25
(S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin (Cay-13013), which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (-)-Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5...
Keywords: | S-(-)-7-Desmethyl-8-nitro Blebbistatin, (3aS)-1,2,3,3a-tetrahydro-3a-hydroxy-7-nitro-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one |
Application: | Photostable (-)-blebbistatin analog, non-muscle myosin II ATPase inhibitor |
CAS | 856925-75-2 |
MW: | 323.3 D |
From 158.00€
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Item number: Cay13876-25
Alexidine is an alkyl bis(biguanide) antiseptic which has been used in mouthwashes to eliminate plaque forming microorganisms. It binds to lipopolysaccharide and lipoteichoic acid and inhibits fungal phospholipase B (IC50 ~ 250 nM). Alexidine also inhibits the mitochondrial phosphatase PTPMT1 (IC50 = 1.08 µM, in...
Keywords: | N1,N14-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide, dihydrochloride |
Application: | Antiseptic |
CAS | 1715-30-6 |
MW: | 581.7 D |
From 43.00€
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