4 products were found matching "Cay13820"!

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Item number: Cay13820-25

Misoprostol is an analog of prostaglandin E1 (PGE1, Cay-13010) and an agonist of the PGE2 receptor subtypes EP2 and EP3. It binds to EP1, EP2, EP3-III, and EP4 receptors (Kis = 35.675, 10.249, 0.319, 5.499 µM, respectively) and is selective for EP receptors over DP, FP, IP, and TP receptors (Kis = >100 µM for all)....

Keywords:	SC 29333, 9-oxo-11alpha,16-dihydroxy-16-methyl-prost-13E-en-1-oic acid, methyl ester
Application:	EP receptor agonist
CAS	59122-46-2
MW:	382.5 D

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Resolvin E2

Item number: Cay13827-10

Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids. It is produced from eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908) via an 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA, by 5-lipoxygenase (5-LO) in...

Keywords:	RvE2, 5S,18R-dihydroxy-6E,8Z,11Z,14Z,16E-eicosapentaenoic acid
Application:	SPM, specialized pro-resolving mediator
CAS	865532-70-3
MW:	334.5 D

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3-Deazaneplanocin A

Item number: Cay13828-10

3-Deazaneplanocin A is a cyclopentenyl analog of 3-deazaadenosine, originally synthesized as an inhibitor of S-adenosyl-L-homocysteine hydrolase. It has been shown to deplete EZH2 levels and to inhibit trimethylation of lysine 27 on histone H3 in cultured human acute myeloid leukemia (AML) HL-60 and OCI-AML3 cells...

Keywords:	DZNep, NSC 617989, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol
Application:	S-adenosyl-L-homosysteine hydrolase inhibitor
CAS	102052-95-9
MW:	262.3 D

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Misoprostol (free acid)

Item number: Cay13821-50

Misoprostol is a prostaglandin E1 (Cay-13010) analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 µg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 µM), and relax fetal rabbit ductus arteriosus...

Keywords:	9-oxo-11alpha,16-dihydroxy-16-methyl-prost-13E-en-1-oic acid
Application:	EP receptor agonist
CAS	112137-89-0
MW:	368.5 D

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