- Search results for Cay13810
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12 products were found matching "Cay13810"!
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Item number: Cay13810-1
Limaprost is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is orally active in both rats and guinea pigs at doses of 100 µg/kg as an inhibitor of ADP and collagen induced platelet aggregation. Limaprost is 10-1,000 times more potent than PGE1...
Keywords: | 17alpha,20-dimethyl-Delta2-PGE1, 17alpha,20-dimethyl-Delta2-Prostaglandin E1,... |
Application: | PGE1 analog |
CAS | 74397-12-9 |
MW: | 380.5 D |
From 109.00€
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Item number: Cay13338-10
The Src family of proto-oncogenic kinases include nine mammalian non-receptor tyrosine kinases that are involved in intracellular signaling and are often relevant to carcinogenesis. SU6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). It weakly...
Keywords: | 2,3-dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
Application: | Src kinase inhibitor |
CAS | 330161-87-0 |
MW: | 371.5 D |
From 32.00€
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Item number: Cay13388-10
2-amino-4-phenyl Thiazole is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 4-phenyl-2-thiazolamine. CAS Number: 2010-06-2. Synonyms: NSC 2528. Molecular Formula: C9H8N2S. Formula Weight: 176.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF:...
Keywords: | NSC 2528, 4-phenyl-2-thiazolamine |
Application: | Synthetic intermediate, pharmaceutical synthesis |
CAS | 2010-06-2 |
MW: | 176.2 D |
From 30.00€
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Item number: Cay13834-10
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response. Resolvin D3 (RvD3) is a DHA-derived product first identified in...
Keywords: | RvD3, 4S,11R,17S-trihydroxy-5Z,7E,9E,13Z,15E,19Z-docosahexaenoic acid |
Application: | Antiinflammatory lipid mediator |
CAS | 916888-47-6 |
MW: | 376.5 D |
From 205.00€
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Item number: Cay13857-10
Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...
Keywords: | NSC 238159, Oncodazole, R 17934, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
Application: | Microtubule function studies, cell cycle arrest |
CAS | 31430-18-9 |
MW: | 301.3 D |
From 48.00€
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Item number: Cay13804-10
gamma-Glutamyl transferase (GGT) is involved in the transfer of amino acids across the plasma membrane as well as in glutathione metabolism. Serum GGT activity is commonly used as a marker of liver dysfunction and alcohol abuse. It is also useful as a biomarker of type 2 diabetes and cardiovascular disease. OU749 is...
Keywords: | N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-benzenesulfonamide |
Application: | gamma-Glutamyl transferase inhibitor |
CAS | 519170-13-9 |
MW: | 361.4 D |
From 31.00€
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COVID-19 Research
Item number: Cay13872-10
Ritonavir is an HIV protease inhibitor. It inhibits recombinant HIV-1 protease by 79% when used at a concentration of 0.5 nM. It inhibits HIV-13B-induced cell death in MT-4 human T cell leukemia cells (EC50 = 25 nM) as well as cell death induced by HIV-1LAI, HIV-2ROD, and HIV-2EHO in human MT-2 cells (IC50s = 0.045,...
Keywords: | A-84538, ABT-538, NSC 693184, RTV,... |
Application: | Antiviral, HIV protease inhibitor |
CAS | 155213-67-5 |
MW: | 720.9 D |
From 38.00€
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Item number: Cay13889-10
JWH 018 is a synthetic cannabinoid which has been identified in smoking mixtures. JWH 018 N-(4-oxo-pentyl) metabolite is a potential metabolite of JWH 018 that is characterized by a carbonyl group at the 4 position of the alkyl chain. Its biological and toxicological properties are not known. This product is...
Keywords: | JWH 018 4-keto metabolite, 5-(3-(1-naphthoyl)-1H-indol-1-yl)pentan-2-one |
Application: | Analytical reference standard, Potential JWH 018 metabolite |
CAS | 2748474-41-9 |
MW: | 355.4 D |
From 158.00€
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Item number: Cay13898-10
A-836339 (Cay-13898) is a synthetic cannabinoid (CB) which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 receptor (Ki = 270 nM). It displays analgesic, anti-inflammatory, and anti-hyperalgesic effects in mice. At higher doses, A-836339 also decreases spontaneous locomotor...
Keywords: | [N(Z)]-N-[3-(2-methoxyethyl)-4,5-dimethyl-2(3H)-thiazolylidene]-2,2,3,3-tetramethyl-cyclopropanecarboxamide |
Application: | Analytical reference standard, synthetic cannabinoid, analgesic, antiinflammatory, antihyperalgesic |
CAS | 959746-77-1 |
MW: | 310.5 D |
From 109.00€
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Item number: Cay13875-10
Valganciclovir is a valyl ester prodrug form of the antiviral nucleoside analog ganciclovir (Cay-13853). In vivo, valganciclovir (200 mg/kg) increases survival and reduces weight loss in an immunosuppressed hamster model of disseminated adenovirus type 5 (Ad5) infection. Formulations containing valganciclovir have...
Keywords: | Ro 107-9070/194, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester L-valine, monohydrochloride |
Application: | Ganciclovir prodrug, DNA polymerase inhibitor |
CAS | 175865-59-5 |
MW: | 390.8 D |
From 84.00€
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Item number: Cay13878-10
KL001 is a cryptochrome protein stabilizer. It inhibits ubiquitin-induced degradation of cryptochrome 1 (CRY1) in HEK293T cells overexpressing CRY1 when used at a concentration of 50 µM. KL001 (0.3-24 µM) lengthens the circadian period in U2OS human osteosarcoma cells in a reporter assay. It reduces glucagon-induced...
Keywords: | N-[3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)-methanesulfonamide |
Application: | CRY1/CRY2 stabilizer |
CAS | 309928-48-1 |
MW: | 398.5 D |
From 92.00€
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Item number: Cay13831-10
Entecavir is an antiviral nucleoside analog of 2'-deoxyguanosine (Cay-9002864) and inhibitor of hepatitis B virus (HBV) reverse transcriptase (IC50 = 0.5 nM). It undergoes phosphorylation by cellular kinases to its active form, entecavir triphosphate. Entecavir reduces virion DNA in the culture supernatant of HepG2...
Keywords: | BMS 200475, SQ 34,676,... |
Application: | Deoxyguanosine nucleoside analog |
CAS | 209216-23-9 |
MW: | 295.3 D |
From 84.00€
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