- Search results for Cay13800
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14 products were found matching "Cay13800"!
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Item number: Cay13884-100
Puromycin is a derivative of the glomerular epithelial cell toxin puromycin aminonucleoside (Cay-15509) and an inhibitor of protein synthesis that has been found in S. alboniger. Puromycin is structurally similar to the amino acid-bearing end of tRNA, which allows it to enter the ribosome during protein synthesis,...
Keywords: | CL 13,900, CL 16,536, NSC 3055, PDH, 3'-[[2S-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine,... |
Application: | Aminonucleosid antibiotic |
CAS | 58-58-2 |
MW: | 544.4 D |
From 50.00€
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Item number: Cay13804-10
gamma-Glutamyl transferase (GGT) is involved in the transfer of amino acids across the plasma membrane as well as in glutathione metabolism. Serum GGT activity is commonly used as a marker of liver dysfunction and alcohol abuse. It is also useful as a biomarker of type 2 diabetes and cardiovascular disease. OU749 is...
Keywords: | N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-benzenesulfonamide |
Application: | gamma-Glutamyl transferase inhibitor |
CAS | 519170-13-9 |
MW: | 361.4 D |
From 31.00€
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Item number: Cay13828-500
3-Deazaneplanocin A is a cyclopentenyl analog of 3-deazaadenosine, originally synthesized as an inhibitor of S-adenosyl-L-homocysteine hydrolase. It has been shown to deplete EZH2 levels and to inhibit trimethylation of lysine 27 on histone H3 in cultured human acute myeloid leukemia (AML) HL-60 and OCI-AML3 cells...
Keywords: | DZNep, NSC 617989, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol |
Application: | S-adenosyl-L-homosysteine hydrolase inhibitor |
CAS | 102052-95-9 |
MW: | 262.3 D |
From 130.00€
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Item number: Cay13812-500
17beta-hydroxy Wortmannin is an analog of wortmannin. It irreversibly binds phosphoinositide 3-kinase (PI3K) and potently blocks fMLP-stimulated respiratory burst in neutrophils (IC50 = 5 nM). 17beta-hydroxy Wortmannin inhibits recombinant PI3K and mTOR (IC50 = 2.7 and 193 nM, respectively) and prevents the growth...
Keywords: | 17beta-hydroxy-11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]inde... |
Application: | PI3K inhibitor |
CAS | 58053-83-1 |
MW: | 430.4 D |
From 80.00€
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Item number: Cay13832-500
trans-Resveratrol-3-O-beta-D-glucuronide is a stilbene that has been found in red wine and an active metabolite of trans-resveratrol (Cay-70675), a polyphenol with diverse biological activities. It is primarily produced from trans-resveratrol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1....
Keywords: | Resveratrol 3-O-D-Glucuronide, 3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl-beta-D-glucopyranosiduronic acid |
Application: | Metabolic studies |
CAS | 387372-17-0 |
MW: | 404.4 D |
From 163.00€
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Item number: Cay13823-500
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes. AX 048 is a potent group IVA cPLA2 inhibitor that demonstrates 50%...
Keywords: | 4-[(1,2-dioxohexadecyl)amino]-butanoic acid, ethyl ester |
Application: | cPLA2 inhibitor |
CAS | 873079-69-7 |
MW: | 383.6 D |
From 189.00€
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Item number: Cay13825-500
Misoprostol is a widely sold analog of prostaglandin E1 (PGE1) which has potent but relatively non-selective agonist activity with respect to the prostanoid EP receptor subgroup. Misoprostol has been used therapeutically for many years in humans for the treatment of gastric ulcer disease under the Searle tradename...
Keywords: | 9-oxo-11beta,16-dihydroxy-16-methyl-prost-13E-en-1-oic acid, methyl ester |
Application: | Bioactive lipid assays |
CAS | 58717-36-5 |
MW: | 382.5 D |
From 236.00€
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Item number: Cay13834-100
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response. Resolvin D3 (RvD3) is a DHA-derived product first identified in...
Keywords: | RvD3, 4S,11R,17S-trihydroxy-5Z,7E,9E,13Z,15E,19Z-docosahexaenoic acid |
Application: | Antiinflammatory lipid mediator |
CAS | 916888-47-6 |
MW: | 376.5 D |
From 205.00€
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Item number: Cay13835-100
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Cay-90310). It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines. RvD4, at 10 ng/mouse, reduces neutrophil...
Keywords: | RvD4, (4S,5R,6E,8E,10Z,13Z,15E,17S,19Z)-4,5,17-trihydroxy-6,8,10,13,15,19-docosahexaenoic acid |
CAS | 1025684-60-9 |
MW: | 376.5 D |
From 205.00€
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Item number: Cay13875-100
Valganciclovir is a valyl ester prodrug form of the antiviral nucleoside analog ganciclovir (Cay-13853). In vivo, valganciclovir (200 mg/kg) increases survival and reduces weight loss in an immunosuppressed hamster model of disseminated adenovirus type 5 (Ad5) infection. Formulations containing valganciclovir have...
Keywords: | Ro 107-9070/194, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester L-valine, monohydrochloride |
Application: | Ganciclovir prodrug, DNA polymerase inhibitor |
CAS | 175865-59-5 |
MW: | 390.8 D |
From 84.00€
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Item number: Cay13831-100
Entecavir is an antiviral nucleoside analog of 2'-deoxyguanosine (Cay-9002864) and inhibitor of hepatitis B virus (HBV) reverse transcriptase (IC50 = 0.5 nM). It undergoes phosphorylation by cellular kinases to its active form, entecavir triphosphate. Entecavir reduces virion DNA in the culture supernatant of HepG2...
Keywords: | BMS 200475, SQ 34,676,... |
Application: | Deoxyguanosine nucleoside analog |
CAS | 209216-23-9 |
MW: | 295.3 D |
From 84.00€
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COVID-19 Research
Item number: Cay13854-100
Lopinavir is a potent HIV-1 protease inhibitor (Ki = 1.3 pM for wild-type enzyme). It inhibits the replication of clinical isolates of HIV-1 (EC50s = 5-52 nM). Lopinavir reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with severe acute respiratory...
Keywords: | A-157378.0, ABT-378,... |
Application: | HIV-1 protease inhibitor |
CAS | 192725-17-0 |
MW: | 628.8 D |
From 50.00€
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