- Search results for Cay13760
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8 products were found matching "Cay13760"!
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Item number: Cay13967-10
DOT1L is a protein methyltransferase (PMT). It is the only enzyme known to methylate histone 3 at lysine 79 (H3K79), where it catalyzes mono-, di-, and trimethylation. Proper DOT1L function is necessary for transcriptional activation of many genes, DNA damage repair, and cell cycle regulation. SGC0946 is a potent...
Keywords: | 5-bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-beta-D-ribofura... |
Application: | Potent DOT1L inhibitor |
CAS | 1561178-17-3 |
MW: | 618.6 D |
From 129.00€
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Item number: Cay13667-10
The amino acid gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that acts through two families of heteromeric ligand-gated ion channels, GABAA and GABAC and a G protein-coupled receptor, GABAB. Muscimol is a full GABAA agonist and partial GABAC agonist. It binds GABAA on both high- and low-affinity...
Keywords: | Agarin, Pantherine, 5-(aminomethyl)-3(2H)-isoxazolone |
Application: | GABAA agonist |
CAS | 2763-96-4 |
MW: | 114.1 D |
From 98.00€
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Item number: Cay13367-50
(±)17(18)-EpETE methyl ester is an analog of the eicosapentaenoic acid (EPA) metabolite (±)17(18)-EpETE (Cay-50861) that is more lipid soluble.Formal Name: (±)17,18-epoxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid, methyl ester. CAS Number: 141339-46-0. Synonyms: (±)17,18-EEQ methyl ester, (±)17,18-epoxy Eicosatetraenoic...
Keywords: | (±)17,18-EEQ methyl ester, (±)17,18-epoxy Eicosatetraenoic Acid methyl ester,... |
Application: | More lipid soluble methyl ester |
CAS | 141339-46-0 |
MW: | 332.5 D |
From 65.00€
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Item number: Cay13067-10
Mitogen-activated protein kinases (MAPK) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the...
Keywords: | PB 203580, RWJ 64809, 4-[4-(4-fluorophenyl)-2-[4-methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine |
Application: | p38 MAPK inhibitor |
CAS | 152121-47-6 |
MW: | 377.4 D |
From 92.00€
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Item number: Cay13576-10
PIKfyve is a phosphoinositide kinase (PIK) that contains a FYVE-type zinc finger domain, which binds phosphatidylinositol 3-phosphate (PI3P). PIKfyve phosphorylates PI3P to produce PI-(3,5)-P2, which is involved in cellular processes including membrane trafficking and cytoskeletal reorganization. YM-201636 is a...
Keywords: | 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide |
Application: | PIKfyve inhibitor |
CAS | 371942-69-7 |
MW: | 467.5 D |
From 68.00€
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Item number: Cay16763-500
Creatinine-d3 is intended for use as an internal standard for the quantification of creatinine (Cay-31164) by GC- or LC-MS. Creatinine is synthesized in kidney, liver, and pancreas and transported in blood to muscle and brain where it is phosphorylated to phosphocreatine. Some free creatine in muscle is converted to...
Keywords: | 2-amino-1,5-dihydro-1-(methyl-d3)-4H-imidazol-4-one |
Application: | Internal standard |
CAS | 143827-20-7 |
MW: | 116.1 D |
From 60.00€
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Item number: Cay11763-500
Vincamine is an indole alkaloid found in the leaves of V. minor and C. roseus that is used as a peripheral vasodilator to increase blood flow to the brain. Vincamine contracts excised human cerebrovascular smooth muscle in vitro with an EC50 value of 30 µM and has been explored as a pharmacotherapy to treat cerebral...
Keywords: | Angiopac, Devincan, Equipur, Minorin, Novicet, NSC 91998, Oxybral, Perval, Sostenil, Tripervan,... |
Application: | Cerebral vasodilator, plant alkaloid |
CAS | 1617-90-9 |
MW: | 354.4 D |
From 66.00€
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Item number: Cay13076-5
Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM. Most preparations of...
Keywords: | 6,9alpha-methylene-11alpha,15S-dihydroxy-16R-methyl-prosta-5E,13E-dien-18-yn-1-oic acid |
Application: | PGI2 analog |
CAS | 74843-13-3 |
MW: | 360.5 D |
From 201.00€
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