- Search results for Cay13752-%25
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6 products were found matching "Cay13752-%25"!
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Item number: Cay14735-25
Salubrinal is a selective phosphatase inhibitor that prevents dephosphorylation of eukaryotic translation initiation factor 2 subunit alpha (eIF2alpha), protecting PC12 cells from endoplasmic reticulum stress-mediated apoptosis (EC50 = 15 µM). It appears to block the action of protein phosphatase 1 (PP1) on...
Keywords: | (2E)-3-phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide |
Application: | eIF2alpha dephosphorylation (PP1) inhibitor |
CAS | 405060-95-9 |
MW: | 479.8 D |
From 35.00€
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Item number: Cay11732-25
O6-Methylguanine-DNA methyltransferase (MGMT) (Cay-11176) is a DNA repair protein which removes an alkyl group from the O6 position on guanine in an autoinactivating reaction. Although important in normal DNA repair, this reaction confers resistance to treatments that use O6-alkylating agents to produce...
Keywords: | PaTrin 2, 6-[(4-bromo-2-thienyl)methoxy]-9H-purin-2-amine |
Application: | MGMT inhibitor |
CAS | 192441-08-0 |
MW: | 326.2 D |
From 52.00€
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Item number: Cay15375-25
Arctiin is the major active lignin in fruits of the burdock plant A. lappa. It demonstrates potent antiviral activity against influenza A virus and anti-inflammatory effects by decreasing the production of nitric oxide and pro-inflammatory cytokines. Arctiin is metabolized by human intestinal bacteria into various...
Keywords: | Arctigenin-4-Glucoside, NSC 315527,... |
Application: | Antiviral |
CAS | 20362-31-6 |
MW: | 534.6 D |
From 84.00€
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Item number: Cay19375-25
Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
Keywords: | E-7080, ER-203492-00, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide |
Application: | VEGFR / FGFR / PDGFR inhibitor |
CAS | 417716-92-8 |
MW: | 426.9 D |
From 43.00€
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Item number: Cay13875-25
Valganciclovir is a valyl ester prodrug form of the antiviral nucleoside analog ganciclovir (Cay-13853). In vivo, valganciclovir (200 mg/kg) increases survival and reduces weight loss in an immunosuppressed hamster model of disseminated adenovirus type 5 (Ad5) infection. Formulations containing valganciclovir have...
Keywords: | Ro 107-9070/194, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester L-valine, monohydrochloride |
Application: | Ganciclovir prodrug, DNA polymerase inhibitor |
CAS | 175865-59-5 |
MW: | 390.8 D |
From 84.00€
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Item number: Cay33157-25
Tetrahydroberberine is an isoquinoline alkaloid that has been found in C. turtschaninovii and has diverse biological activities. It inhibits iron- and ascorbate-induced lipid peroxidation in rat liver microsomes (IC50 = 13.7 µM). Tetrahydroberberine binds to dopamine D2 receptors and the serotonin (5-HT) receptor...
Keywords: | (±)-Tetrahydroberberine, Canadine, NSC 36351, NSC 94918, Xanthopuccine,... |
Application: | Bioactive isoquinoline alkaloid |
CAS | 522-97-4 |
MW: | 339.4 D |
From 44.00€
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