- Search results for Cay13746-%25
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
7 products were found matching "Cay13746-%25"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay13647-25
AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50 = 0.36 nM). AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spindle checkpoint functions and chromosome alignment, resulting in inhibition of cytokinesis...
Keywords: | Barasertib,... |
Application: | Aurora kinase B inhibitor prodrug |
CAS | 722543-50-2 |
MW: | 660.5 D |
From 32.00€
*
Item number: Cay37461-25
LRRKtide is a peptide substrate for leucine-rich repeat kinase 2 (LRRK2), an enzyme frequently mutated in patients with Parkinson's disease, that corresponds to amino acids 550-564 of membrane-organizing extension spike protein (moesin). It has been used to identify inhibitors of LRRK2.Formal Name:...
Keywords: | Membrane-organizing Extension Spike Protein (550-564), Moesin (550-564),... |
Application: | LRRK2 peptide substrate |
MW: | 1931.3 D |
From 122.00€
*
Item number: Cay13346-5
Rapamycin is an allosteric inhibitor of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) originally isolated from S. hygroscopicus. It interacts with FKBP prolyl isomerase 1A (FKBP12) to form a complex that binds to and inhibits the kinase activity of mTORC1. Rapamycin inhibits growth of Rh1 and Rh30...
Keywords: | AY 22989, NSC 226080, Wy 090217,... |
Application: | mTORC1 blocking |
CAS | 53123-88-9 |
MW: | 914.2 D |
From 50.00€
*
Item number: Cay14736-25
WP1066 is a cell-permeable inhibitor of STAT3 that directs dephosphorylation and nuclear export of constitutively phosphorylated STAT3 in U87-MG and U373-MG malignant glioma cells when given at a concentration of 10 µM. It also induces apoptosis in U87-MG (IC50 = 5.6 µM) and U373-MG (IC50 = 3.7 µM) cells. WP1066 is...
Keywords: | STAT Inhibitor III, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylethyl]-2E-propenamide |
Application: | STAT3 inhibitor |
CAS | 857064-38-1 |
MW: | 356.2 D |
From 43.00€
*
Item number: Cay16374-25
alpha-Hydroxyglutaric acid (2-HG) is an alpha-hydroxy acid. It is metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases, and mutations in these enzymes lead to 2-hydroxyglutaric aciduria, a neurometabolic disorder characterized by increased levels of L-2-hydroxyglutaric acid (Cay-21123). 2-HG...
Keywords: | 2-HG, 2-Hydroxyglutaric Acid, 2-hydroxy-pentanedioic acid, disodium salt |
Application: | alpha-ketoglutarate-dependent dioxygenase inhibitor |
CAS | 40951-21-1 |
MW: | 192.1 D |
From 66.00€
*
Item number: Cay31746-25
(±)15-HETE-d8 is intended for use as an internal standard for the quantification of 15-HETE by GC- or LC-MS. (±)15-HETE and 15(S)-HETE are formed via non-enzymatic and 15-lipoxygenase-mediated oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607), respectively. 15(R)-HETE is formed by...
Keywords: | 15-hydroxyicosa-5Z,8Z,11Z,13Z-tetraenoic-5,6,8,9,11,12,14,15-d8 acid |
Application: | GC-MS, LC-MS, internal standard, quantification |
CAS | 2525175-31-7 |
MW: | 328.5 D |
From 196.00€
*
Item number: Cay17346-25
Progeria is a genetic disorder that results in the appearance of premature aging. Genetically, progeria is characterized by a mutation in lamin A, which results in misshapen cell nuclei and DNA damage. Remodelin is a 2-thiazolylhydrazone derivative that, at 10 µM, improves nuclear architecture, chromatin...
Keywords: | 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile |
Application: | NAT10 inhibitor |
CAS | 949912-58-7 |
MW: | 282.4 D |
From 66.00€
*