- Search results for Cay13738-%25
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3 products were found matching "Cay13738-%25"!
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Item number: Cay17383-25
AMG 319 is a potent inhibitor of phosphatidylinositol 3-kinase (PI3K) isoform delta (PI3Kdelta, IC50 = 18 nM) that less effectively targets the alpha, beta, and gamma isoforms (IC50s = 33, 2.7, and 0.85 µM, respectively). It blocks anti-IgM/CD40L-induced proliferation (IC50 = 8.6 nM) and reduces Akt phosphorylation...
Keywords: | 7-fluoro-alphaS-methyl-N-9H-purin-6-yl-2-(2-pyridinyl)-3-quinolinemethanamine |
Application: | PI3K delta inhibitor |
CAS | 1608125-21-8 |
MW: | 385.4 D |
From 43.00€
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Item number: Cay13838-25
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3, important second messengers that modulate the activity of downstream targets Akt and mTOR. Aberrant PI3K/Akt is associated with many human cancers. CAY10626 is a...
Keywords: | N-[2-(dimethylamino)ethyl]-N-methyl-4-[[[[4-[4-(4-morpholinyl)-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]ph... |
Application: | PI3K inhibitor |
CAS | 1202884-94-3 |
MW: | 624.7 D |
From 141.00€
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Item number: Cay13338-25
The Src family of proto-oncogenic kinases include nine mammalian non-receptor tyrosine kinases that are involved in intracellular signaling and are often relevant to carcinogenesis. SU6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). It weakly...
Keywords: | 2,3-dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
Application: | Src kinase inhibitor |
CAS | 330161-87-0 |
MW: | 371.5 D |
From 32.00€
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