8 products were found matching "Cay13734-%25"!

Chlorhexidine is a bis(biguanide) antimicrobial disinfectant and antiseptic agent. It inhibits growth of clinical methicillin-resistant S. aureus (MRSA) isolates (MIC90 = 4 µg/ml). It is also active against canine isolates of MRSA, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. pseudintermedius...

CAY10734 is an agonist of sphingosine-1-phosphate receptor 1 (S1P1, IC50 = 0.6 nM). It selectively binds S1P1 over S1P2, S1P3, and S1P4 receptors (IC50s = >10,000, 12,000, and 70 nM, respectively) but does also bind S1P5 receptors (IC50 = 1 nM) in radioligand binding assays. CAY10734 reduces the number of peripheral...

BRD0705 is an inhibitor of glycogen synthase kinase 3alpha (GSK3alpha, IC50 = 66 nM). It is selective for GSK3alpha over GSK3beta (IC50 = 515 nM). BRD0705 (10 and 20 µM) inhibits GSK3alpha autophosphorylation in U937 cells. It impairs colony formation of MOLM-13, TF-1, U937, MV4-11, HL-60, and NB4 acute myeloid...

Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. It accumulates in these abnormal blood vessels and, when activated by nonthermal red light with a wavelength of 693 nm in the presence of...

The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. PD 0325901 is a potent MEK inhibitor that suppresses phosphorylation of ERK in mouse colon 26 tumors with an IC50 value of 0.33 nM. Suppression of ERK activation...

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response. Resolvin D3 (RvD3) is a DHA-derived product first identified in...

DC4 crosslinker is a mass spectrometry-cleavable crosslinking reagent (18Å in length) that contains two intrinsic positive charges, which allow cross-linked peptides to fragment into their component peptides by collision-induced dissociation or in-source decay. Initial fragmentation events result in cleavage on...

Streptavidin conjugated to SureLight(R) R-PE Binding Moiety: Streptavidin Dye: SureLight(R) R-PE Excitation max. lambda: 565 > 540 > 498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, fluorescence-activated cell sorting, and luminex Important Features of SureLight(TM) Polymeric SAPE (high-intensity):  8-10x...