8 products were found matching "Cay13734"!

Rabbit Anti-V5 IgG conjugated to Biotin Antibody: Rabbit polyclonal anti-V5 Binding Moiety: Biotin Uses: ELISA, microscopy, and Western blot detection Reactivity: V5-tagged proteins Immunogen: V5 (GKPIPNPLLGLDST) Recommended dilution of 1:500 - 1:10000. Starting dilution: 1:2000Formulation: (Request formulation...

IBMX is a widely-used non-specific inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) (IC50 = 19, 50, 18, 13, 32, 7, and 50 µM for PDE1, PDE2, PDE3, PDE4, PDE5, PDE7, and PDE11, respectively). PDE8A, PDE8B, and PDE9 are insensitive to IBMX. By inhibiting PDEs, IBMX increases cellular cAMP and cGMP...

Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. It accumulates in these abnormal blood vessels and, when activated by nonthermal red light with a wavelength of 693 nm in the presence of...

AM694 N-pentanoic acid metabolite-d5 is intended for use as an internal standard for the quantification of AM694 N-pentanoic acid metabolite by GC- or LC-MS. AM694 (Cay-10567) is a potent synthetic cannabinoid (CB) with Ki values of 0.08 and 1.44 nM for the central CB1 and peripheral CB2 receptors, respectively....

Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination, and methylation. These modifications play critical roles in regulating chromatin structure and gene...

Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB...

15(S)-15-methyl Prostaglandin E1 (15(S)-15-methyl PGE1) is a metabolically stable synthetic analog of PGE1 (Cay-13010). In sharp contrast to the bronchodilatory effects of PGE1, 15(S)-15-methyl PGE1 is a weak constrictor of human respiratory tract smooth muscle.Formal Name:...

Fibroblast growth factor 1 (FGF1), also known as acidic FGF (AFGF), is a signaling polypeptide and member of the FGF family with roles in cell growth, proliferation, development, and survival, as well as osteogenesis and adipogenesis. Unlike other FGFs, FGF1 lacks an N-terminal signaling peptide and is secreted via...