10 products were found matching "Cay13723-%25"!

1,2-Didocosahexaenoyl-sn-glycero-3-PC is a phospholipid that contains docosahexaenoic acid (Cay-90310, Cay-17950) at the sn-1 and sn-2 positions. It has been used in the formation of polyunsaturated endoplasmic reticulum-targeting liposomes (PERLs) that reduce cellular cholesterol levels in human peripheral blood...

PPM-18 is a naphthoquinone compound that inhibits NF-kappaB activation in vitro and in vivo (IC50 = 5 µM). Through this action, it inhibits the expression of inducible nitric oxide synthase (iNOS) in macrophages treated with lipopolysaccharide and suppresses inflammation and sepsis.Formal Name:...

D609 is a xanthate and a competitive inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC, Ki = 6.4 µM). It has no effect on bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D. D609 reduces sphingomyelin synthase activity by 55.5 and 90.5% in membrane preparations...

ST638 is a tyrosine kinase inhibitor (IC50 = 370 nM). It suppresses tyrosine phosphorylation induced by tumor necrosis factor-alpha and phorbol myristate acetate in neutrophils and by angiotensin II in cardiac fibroblasts.Formal Name: 2-cyano-3-[3-ethoxy-4-hydroxy-5-[(5-phenylthio)methyl]phenyl]-2-propenamide. CAS...

(±)17(18)-EpETE methyl ester is an analog of the eicosapentaenoic acid (EPA) metabolite (±)17(18)-EpETE (Cay-50861) that is more lipid soluble.Formal Name: (±)17,18-epoxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid, methyl ester. CAS Number: 141339-46-0. Synonyms: (±)17,18-EEQ methyl ester, (±)17,18-epoxy Eicosatetraenoic...

Tioxolone is an inhibitor of carbonic anhydrase I (CAI, Ki = 91 nM). It is selective for CAI over CAII, -III, -IV, -VA, -VB, -VI, -VII, -IX, -XII, and -XIV (Kis = 4,930-9,040 nM). Tioxolone is active against Gram-positive or -negative bacteria, including M. tuberculosis. It is also active against dermatophytes,...

4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA (Cay-90310) with antiproliferative and PPARgamma agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 µM, however it increased proliferation of MCF-7...

Temoporfin is a synthetic chlorin with light-activated actions. When administered systemically, temoporfin accumulates in tumor cells. When stimulated with light (650-652 nm) in the presence of oxygen, reactive oxygen species are generated, leading to necrosis within the tumor. Different approaches to using...

Chromobox homolog 7 (CBX7) functions through its N-terminal chromodomain, which recognizes histone 3 trimethyl lysine 27 (H3K27me3), to repress gene transcription. It plays a key role in gene transcription in cellular processes related to stem cell self-renewal and differentiation, as well as tumor progression....

7-fluoro Tryptamine is a tryptamine derivative that potentially agonizes 5-HT serotonin receptors. Although the biological effects of this compound have not been reported, certain hallucinogenic typtamines containing a fluorine substitution at the 5-, 6-, or 7-position have been shown to have 5-HT2C receptor...