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Item number: Cay13197-25

gamma-Secretase is a multi-subunit aspartyl protease that cleaves amyloid precursor protein (APP) and many other type 1 transmembrane proteins, including Notch, E-cadherin, and ErbB4. The proteolysis of APP by secretases produces beta amyloid (Abeta), a 39- to 42-amino acid peptide which forms the amyloid plaques...

Keywords:	GSI-IX, N-[2S-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-glycine, 1,1-dimethylethyl ester
Application:	gamma-secretase inhibitor
CAS	208255-80-5
MW:	432.5 D

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