- Search results for Cay13718
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14 products were found matching "Cay13718"!
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Item number: Cay13871-1
TAK-242 is an antagonist of toll-like receptor 4 (TLR4) with an IC50 value of 0.68 µM in a secreted alkaline phosphatase (SEAP) assay. It selectively binds to TLR4 over TLR1-3 and TLR5-10 when used at a concentration of 100 nM. TAK-242 (1 µM) prevents the interaction of TLR4 with its adaptor proteins TIRAP or TRAM...
Keywords: | Resatorvid, 6R-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-1-cyclohexene-1-carboxylic acid, ethyl ester |
Application: | TLR4 adaptor binding inhibitor |
CAS | 243984-11-4 |
MW: | 361.8 D |
From 98.00€
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Item number: Cay13781-1
Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei. It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various...
Keywords: | Anti-H3FA, Anti-H3FL, Anti-H3FB, Anti-H3FD, Anti-H3FI, Anti-H3FH, Anti-H3FK, Anti-H3FF, Anti-H3FJ, Anti-Histone H3.1,... |
Application: | ELISA, FC, IP, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay14738-10
NNEI (Cay-15001) is a synthetic cannabinoid featuring a naphthalene group joined to an indole carboxamide through the one position. NNEI 2'-naphthyl isomer (Cay-14738) differs from NNEI by having the naphthalene group joined at the two position. The physiological or toxicological properties of this compound have not...
Keywords: | MN-24 2'-naphthyl isomer, N-2-naphthalenyl-1-pentyl-1H-indole-3-carboxamide |
Application: | Analytical reference standard, synthetic cannabinoid analog |
CAS | 1338925-12-4 |
MW: | 356.5 D |
From 109.00€
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Item number: Cay11738-10
LY320135 is a selective cannabinoid (CB) receptor 1 antagonist (Kis = 224 and >10,000 nM for CB1 and CB2, respectively, in vitro). It is selective for CB1 over alpha1- and alpha2- adrenergic, D1 and D2 dopamine, benzodiazepine, histamine H1, GABA, serotonin (5-HT), and muscarinic receptors. It reverses the...
Keywords: | 4-[[6-methoxy-2-(4-methoxyphenyl)-3-benzofuranyl]carbonyl]-benzonitrile |
Application: | Cannabinoid receptor 1 (CB1) antagonist |
CAS | 176977-56-3 |
MW: | 383.4 D |
From 39.00€
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Item number: Cay17738-10
While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which include HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. TMP269 is a cell-permeable inhibitor...
Keywords: | N-[[tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-benzamide |
Application: | Cell-permeable class IIa HDAC inhibitor |
CAS | 1314890-29-3 |
MW: | 514.5 D |
From 50.00€
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Item number: Cay17318-1
5-fluoro Orotic acid (5-FOA) is used to detect URA3 gene expression in yeast molecular genetic constructs. Yeast with an active URA3 gene, which encodes orotidine-5'-monophosphate decarboxylase, converts 5-FOA to fluorodeoxyuridine, which is toxic to cells. Resistant strains of yeast that carry a mutation in the...
Keywords: | 5-fluoro OA, 5-FOA, 5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid, monohydrate |
Application: | URA3 gene expression detection |
CAS | 220141-70-8 |
MW: | 192.1 D |
From 82.00€
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Item number: Cay13178-5
The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to, e.g., longevity, cancer, gene regulation, energy homeostasis, and apoptosis. Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells,...
Keywords: | N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-a-methyl-benzeneacetamide |
Application: | SIRT inhibitor |
CAS | 1105698-15-4 |
MW: | 394.5 D |
From 68.00€
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Item number: Cay13978-1
JWH 149 (Cay-13978) is a synthetic cannabinoid (CB) which potently binds both the central CB1 receptor (Ki = 5.0 nM) and the peripheral CB2 receptor (Ki = 0.73 nM). Its physiological properties have not been elucidated. This product is intended for research and forensic applications.Formal Name:...
Keywords: | (4-methyl-1-naphthalenyl)(2-methyl-1-pentyl-1H-indol-3-yl)-methanone |
Application: | Analytical reference standard, synthetic cannabinoid |
CAS | 548461-82-1 |
MW: | 369.5 D |
From 241.00€
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Item number: Cay14378-1
BB-22 (Cay-14099) is an analog of the potent synthetic cannabinoid, JWH 018 (Cay-10900) that is structurally similar to PB-22 (Cay-14096) and its derivative, 5-fluoro PB-22 (Cay-14095). Both BB-22 and PB-22 are distinctive in that an 8-hydroxyquinoline replaces the naphthalene group of JWH 018. BB-22 3-carboxyindole...
Keywords: | 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid |
Application: | Analytical reference standard, expected BB-22 metabolite (serum/urine ) |
CAS | 858515-71-6 |
MW: | 257.3 D |
From 158.00€
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Item number: Cay16378-1
Cellobiosan is an anhydro sugar formed during biofuel production from the fast pyrolysis of wood.Formal Name: 1,6-anhydro-4-O-beta-D-glucopyranosyl-beta-D-glucopyranose. CAS Number: 35405-71-1. Synonyms: 1,6-Anhydro-beta-cellobiose. Molecular Formula: C12H20O10. Formula Weight: 324.3. Purity: >95%. Formulation:...
Keywords: | 1,6-Anhydro-beta-cellobiose, 1,6-anhydro-4-O-beta-D-glucopyranosyl-beta-D-glucopyranose |
Application: | Wood pyrolysis product |
CAS | 35405-71-1 |
MW: | 324.3 D |
From 109.00€
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Item number: Cay13578-1
Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor I is a potent, cell-permeable inhibitor of mouse VEGFR2...
Keywords: | SU 5408, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid, ethyl ester |
Application: | Mouse VEGFR2 inhibitor |
CAS | 15966-93-5 |
MW: | 310.4 D |
From 92.00€
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Item number: Cay17378-1
AZD 2014 is a potent, selective, ATP-competitive mTORC1/2 dual inhibitor that inhibits phosphorylation of both mTORC1 and 2 substrate proteins in whole cells. It exhibits an IC50 value of 2.81 nM against the isolated recombinant enzyme and >1,000-fold selectivity against all PI3K isoforms. AZD 2014 has broad...
Keywords: | Vistusertib, 3-[2,4-bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-N-methyl-benzamide |
Application: | mTORC1/2 dual inhibitor |
CAS | 1009298-59-2 |
MW: | 462.5 D |
From 43.00€
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