- Search results for Cay13714
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13 products were found matching "Cay13714"!
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Item number: Cay13741-1
Butaprost is an EP2 selective agonist which has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Prostaglandin free acids generally bind to their cognate receptors with 10 to 100 times the affinity of the corresponding ester...
Keywords: | (±)-15-deoxy-16S-hydroxy-17-cyclobutyl PGE1, 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1,... |
Application: | EP2 receptor agonist |
CAS | 433219-55-7 |
MW: | 394.6 D |
From 142.00€
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Item number: Cay10734-10
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. UNC0638 is...
Keywords: | 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine |
Application: | G9a HMTase inhibitor |
CAS | 1255580-76-7 |
MW: | 509.7 D |
From 65.00€
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Item number: Cay14734-10
DC4 crosslinker is a mass spectrometry-cleavable crosslinking reagent (18Å in length) that contains two intrinsic positive charges, which allow cross-linked peptides to fragment into their component peptides by collision-induced dissociation or in-source decay. Initial fragmentation events result in cleavage on...
Keywords: | 1,4-bis[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]-1,4-diazoniabicyclo[2.2.2]octane, dibromide |
Application: | MS-cleavable crosslinking reagent |
CAS | 1374647-94-5 |
MW: | 640.3 D |
From 85.00€
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Item number: Cay13471-1
Rabbit anti-S tag IgG conjugated to Biotin Antibody: Rabbit polyclonal anti-S-tag Binding Moiety: Biotin Uses: ELISA, microscropy, and Western blot detection Reactivity: S-tagged proteins Immunogen: KETAAAKFERQHMDS Recommended dilution of 1:500 - 1:10,000. Starting dilution: 1:2,000.Immunogen: KETAAAKFERQHMDS....
Application: | WB |
Host: | Rabbit |
Species reactivity: | broad |
488.00€
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Item number: Cay13784-1
Histone H3.3 is a nuclear protein and a replication-independent member of the histone H3 family that has a role in nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped...
Keywords: | H3.3A, H3.3B, H3F3A, H3F3B |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | chicken, ovine, Drosophila, equine, human, murine, opossum |
442.00€
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Item number: Cay11437-25
Nigericin is a lipophilic potassium ionophore that has been found in S. hygroscopicus. It mediates neutral antiport of potassium and proton ions across mitochondrial membranes. Nigericin (10 µM) induces T. gondii egress in infected human foreskin fibroblasts (HFFs). It also induces NOD-like receptor protein 3...
Keywords: | NSC 292567,... |
Application: | Metabolic studies |
CAS | 28643-80-3 |
MW: | 747 D |
From 77.00€
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Item number: Cay13174-5
M 344 is an inhibitor of histone deacetylases (HDACs), inhibiting maize HDAC (IC50 = 100 nM) as well as human HDAC1 (IC50 = 46 nM). It shows a three-fold selectivity for inhibition of HDAC6 over HDAC1 (IC50s = 88 and 249 nM, respectively). M 344 enhances the sensitivity of human squamous carcinoma cells to radiation...
Keywords: | D237, Histone Deacetylase Inhibitor III, MS 344, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide |
Application: | HDAC inhibitor |
CAS | 251456-60-7 |
MW: | 307.4 D |
From 88.00€
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Item number: Cay13745-10
Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Serious confusion as to the structure of butaprost was...
Keywords: | (±)-15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester, 15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester, TR 4978,... |
Application: | Bioactive lipid assays |
CAS | 69648-38-0 |
MW: | 408.6 D |
From 181.00€
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Item number: Cay14374-1
UR-144 N-(4-hydroxypentyl) metabolite-d5 (Cay-14374) is intended for use as an internal standard for the quantification of UR-144 N-(4-hydroxypentyl) metabolite by GC- or LC-mass spectrometry (MS). UR-144 (Cay-11502) is a potent synthetic cannabinoid (CB) which preferentially binds the peripheral CB2 receptor (Ki =...
Keywords: | (1-(4-hydroxypentyl)-1H-indol-3-yl-2,4,5,6,7-d5)(2,2,3,3-tetramethylcyclopropyl)methanone |
Application: | Analytical reference standard, GC-MS, LC-MS internal standard, Quantification, Expect. UR-144 metabolite |
CAS | 2747917-78-6 |
MW: | 332.5 D |
From 659.00€
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Item number: Cay19374-1
Ceritinib is an inhibitor of anaplastic lymphoma kinase (ALK, IC50 = 0.2 nM). It is selective for ALK over IGF-1R, InsR, STK22D, and FLT3 (IC50s = 8, 7, 23, and 60 nM, respectively) as well as a panel of 25 additional kinases (IC50s = >0.26 µM for all). Ceritinib inhibits the proliferation of Ba/F3 cells expressing...
Keywords: | LDK 378,... |
Application: | ALK inhibitor |
CAS | 1032900-25-6 |
MW: | 558.1 D |
From 39.00€
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Item number: Cay13574-1
The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases, with AKR1C1 being a 20alpha-HSD and the other three being 3alpha-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin,...
Keywords: | NSC 109116, 5-bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid |
Application: | AKR1C1 inhibitor |
CAS | 4906-68-7 |
MW: | 293.1 D |
From 86.00€
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Item number: Cay17374-1
p53-Binding protein 1 (53BP1) binds to dimethylated lysine 20 on histone 4 (H4K20me2) via tandem tudor domains on a 53BP1 homodimer. This interaction is an important part of the DNA damage response. UNC2170 is a micromolar ligand of 53BP1 that binds to a pocket formed by the tandem tudor domains. It displays at...
Keywords: | 3-bromo-N-[3-[(1,1-dimethylethyl)amino]propyl]-benzamide, 2Z-butenedioate |
Application: | 53BP1 antagonist |
CAS | 2173992-60-2 |
MW: | 429.3 D |
From 65.00€
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