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D609 (potassium salt)
D609 (potassium salt)

Item number: Cay13307-25

D609 is a xanthate and a competitive inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC, Ki = 6.4 µM). It has no effect on bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D. D609 reduces sphingomyelin synthase activity by 55.5 and 90.5% in membrane preparations...
Keywords: Tricyclodecan-9-yl xanthogenate, O-(octahydro-4,7-methano-1H-inden-5-yl) ester, carbonodithioic acid, monopotassium salt
Application: PC-PLC inhibitor
CAS 83373-60-8
MW: 266.5 D
From 50.00€ *
Review
CAY10594
CAY10594

Item number: Cay13207-25

Phospholipase D (PLD) is an enzyme which cleaves the head group from phospholipids, producing the second messenger phosphatidic acid. Two mammalian isoforms of PLD, PLD1 and PLD2, have been identified, with multiple splice variants of each. Although the two isoforms share structural and functional features, they are...
Keywords: N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4,5]dec-8-yl)ethyl]-2-naphthalenecarboxamide
Application: PLD2 inhibitor
CAS 1130067-34-3
MW: 428.5 D
From 68.00€ *
Review