6 products were found matching "Cay13701"!
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Halofuginone (hydrochloride)
Item number: Cay13370-1
Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga. It has antimalarial and anticoccidial actions. In mammals, halofuginone at 10 ng/ml down-regulates Smad3, blocking TGF-beta signaling and preventing both the differentiation of...
| Keywords: | 7-bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone, monohydrochloride |
| Application: | Antiprotozoal, glutamyl-prolyl-tRNA synthetase (EPRS) inhibitor, Smad3 down-regulator |
| CAS | 1217623-74-9 |
| MW: | 451.1 D |
From 163.00€
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Butaprost
Item number: Cay13740-1
Butaprost, a structural analog of PGE2, is a selective agonist for the EP2 receptor subtype. EP2 receptors are expressed on human neutrophils and on respiratory, vascular, and uterine smooth muscle. Butaprost binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor, and does not bind...
| Keywords: | 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1 methyl ester, TR 4979,... |
| Application: | EP2 receptor agonist |
| CAS | 69685-22-9 |
| MW: | 408.6 D |
From 115.00€
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Anti-TRF2 (Clone 4A794.15)
Item number: Cay13790-1
Telomeric repeat binding factor (TRF2) is a ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect...
| Keywords: | Telomeric Repeat Binding Factor 2, TERF2, TRBF2, TTAGGG Repeat Binding Factor 2 |
| Application: | ChIP, ELISA, FC (intracellular), ICC, IF, IHC (frozen/paraffin), IP, WB |
| Host: | Mouse |
| Species reactivity: | human, mouse, rat |
496.00€
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GPP 78
Item number: Cay13670-1
Nicotinamide phosphoribosyltransferase (Nampt) converts nicotinamide into nicotinamide mononucleotide (NMN), which is subsequently converted to NAD+ by NMN adenyltransferase. Cancer cells commonly have an unusually high rate of NAD+ turnover, suggesting that inhibition of Nampt might selectively target cancer cells....
| Keywords: | CAY10618, NMPRTase Inhibitor, N-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)-1H-1,2,3-triazole-1-octanamide |
| Application: | NAMPT inhibitor |
| CAS | 1202580-59-3 |
| MW: | 439.6 D |
From 27.00€
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16,16-dimethyl Prostaglandin E1
Item number: Cay13750-1
16,16-dimethyl PGE1 is a metabolically stable synthetic analog of PGE1. It induces human vascular smooth muscle contractions in vitro. It is 2, 3, and 6 times more potent than PGF2alpha in contracting tracheal, bronchial, and bronchiolar smooth muscle, respectively.Formal Name:...
| Keywords: | 16,16-dimethyl PGE1, 9-oxo-11alpha,15R-dihydroxy-16,16-dimethyl-prost-13E-en-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 41692-15-3 |
| MW: | 382.5 D |
From 98.00€
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15(S)-15-methyl Prostaglandin E1
Item number: Cay13730-1
15(S)-15-methyl Prostaglandin E1 (15(S)-15-methyl PGE1) is a metabolically stable synthetic analog of PGE1 (Cay-13010). In sharp contrast to the bronchodilatory effects of PGE1, 15(S)-15-methyl PGE1 is a weak constrictor of human respiratory tract smooth muscle.Formal Name:...
| Keywords: | 15(S)-15-methyl PGE1, 9-oxo-11alpha,15S-dihydroxy-15-methyl-prost-13E-en-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 35700-26-6 |
| MW: | 368.5 D |
From 125.00€
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