5 products were found matching "Cay13668-%25"!
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Chidamide
Item number: Cay13686-25
Chidamide is an inhibitor of histone deacetylases (HDACs, IC50s = 0.095, 0.160, 0.067, 0.733, 0.078, and 0.432 µM for HDAC1-3, 8, 10, and 11, respectively). It is selective for these HDACs over HDAC4-7 and 9 (IC50s = >30 µM for all). Chidamide also inhibits nicotinamide phosphoribosyltransferase (Nampt, IC50 = 2.1...
| Keywords: | CS 055, HBI 8000, Tucidinostat, N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-benzamide |
| Application: | HDAC inhibitor |
| CAS | 1616493-44-7 |
| MW: | 390.4 D |
From 50.00€
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Muscimol
Item number: Cay13667-25
The amino acid gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that acts through two families of heteromeric ligand-gated ion channels, GABAA and GABAC and a G protein-coupled receptor, GABAB. Muscimol is a full GABAA agonist and partial GABAC agonist. It binds GABAA on both high- and low-affinity...
| Keywords: | Agarin, Pantherine, 5-(aminomethyl)-3(2H)-isoxazolone |
| Application: | GABAA agonist |
| CAS | 2763-96-4 |
| MW: | 114.1 D |
From 98.00€
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YS-121
Item number: Cay13665-25
Microsomal prostaglandin E2 synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever, and pain. 5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs), which are pro-inflammatory mediators. YS-121 is a dual inhibitor of...
| Keywords: | 2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-octanoic acid |
| Application: | mPGES-1/5-LO inhibitor |
| CAS | 916482-17-2 |
| MW: | 408 D |
From 74.00€
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Alfuzosin (hydrochloride)
Item number: Cay13648-25
Alfuzosin is a post-synaptic alpha1-adrenergic receptor antagonist commonly used to improve lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). It displays high-affinity with non-selectivity for the three known human alpha1 adrenoceptors (pKi = 8.0, 8.0, and 8.5 for alpha1A, alpha1B, and...
| Keywords: | SL 77499-10, Uroxatral, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide,... |
| Application: | alpha1-adrenergic receptor antagonist |
| CAS | 81403-68-1 |
| MW: | 425.9 D |
From 60.00€
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CTP354
Item number: Cay36618-25
CTP354 is a deuterated derivative of the GABAA receptor modulator L-838,417. It binds to the GABAA receptor benzodiazepine binding site in non-alpha1 subunit-containing GABAA receptors. CTP354 has a longer duration of action than L-838,417 in a rat model of neuropathic pain induced by sciatic nerve ligation.Formal...
| Keywords: | 3-(2,5-difluorophenyl)-7-[1,1-di(methyl-d3)ethyl-2,2,2-d3]-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-... |
| Application: | Deuterated L-838,417 derivative |
| CAS | 1213669-91-0 |
| MW: | 408.5 D |
From 96.00€
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