11 products were found matching "Cay13661"!

Pregabalin (Cay-13663) is an analytical reference standard categorized as an anticonvulsant and analgesic. Pregabalin has a potential for abuse and misuse. Pregabalin is regulated as a Schedule V compound in the United States. This product is intended for research and forensic applications.Formal Name:...

Microsomal prostaglandin E2 synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever, and pain. 5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs), which are pro-inflammatory mediators. YS-121 is a dual inhibitor of...

Autotaxin is a lysophospholipase D, cleaving lysophosphatidylcholine to produce choline and lysophosphatidic acid (LPA). S32826 is a potent and selective inhibitor of autotaxin, inhibiting recombinant autotaxin beta with an IC50 of 8.8 nM. It shows similar effectiveness against the three known autotaxin isoforms...

Protein S-palmitoylation is the post-translational acylation of proteins and serves to regulate localization, stability, and interaction with associates and substrates. Palmitic acid alkyne is a form of palmitic acid (Cay-10006627) with an omega-terminal alkyne. The terminal alkyne group can be used in linking...

(±)-Warfarin (Cay-13566) is a vitamin K antagonist, a coumarin derivative, and a racemic mixture of (+)-warfarin (Cay-13526) and (-)-warfarin (Cay-13531). It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting...

Chidamide is an inhibitor of histone deacetylases (HDACs, IC50s = 0.095, 0.160, 0.067, 0.733, 0.078, and 0.432 µM for HDAC1-3, 8, 10, and 11, respectively). It is selective for these HDACs over HDAC4-7 and 9 (IC50s = >30 µM for all). Chidamide also inhibits nicotinamide phosphoribosyltransferase (Nampt, IC50 = 2.1...

JWH 398 (Cay-13636) is an analytical reference standard categorized as a synthetic cannabinoid. JWH 398 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.Formal Name: (4-chloro-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-methanone. CAS Number:...

Rabbit anti-S tag IgG conjugated to Alkaline Phosphatase Antibody: Rabbit polyclonal anti-S-tag Enzyme: Alkaline Phosphatase Uses: ELISA and Western blot detection Reactivity: S-tagged proteins Immunogen: KETAAAKFERQHMDS Recommended dilution of 1:500 - 1:10,000. Starting dilution: 1:2,000.Immunogen: KETAAAKFERQHMDS....

Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki = 0.561 nM). AFP...

Gefitinib is an EGFR inhibitor (IC50s = 0.023-0.079 µM). It inhibits colony formation of GEO colon, ZR-75-1 and MCF-10A breast, and OVCAR-3 ovarian cancer cell lines in soft agar assays (IC50s = 0.2-0.4 µM). Gefitinib (0.1 to 1 µM) induces apoptosis and inhibits EGFR autophosphorylation in the same cells. In vivo,...

LSF, a chiral metabolite of pentoxifylline, acts as a potent anti-inflammatory agent. (R)-LSF is the biologically active isomer of LSF. It is a potent inhibitor of the generation of phosphatidic acid (IC50 = 0.6 µM) from cytokine-activated lysophosphatidic acyl transferase (LPAAT), which has been shown to protect...