- Search results for Cay13660
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8 products were found matching "Cay13660"!
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Item number: Cay13660-500
13,14-dihydro-19(R)-hydroxy Prostaglandin E1 (13,14-dihydro-19(R)-hydroxy PGE1) is the theoretical metabolite of 13,14-dihydro PGE1 (Cay-13610) by omega-1 hydroxylase. There are no known reports on its biosynthesis or biological activity.Formal Name: 9-oxo-11alpha,15S,19R-trihydroxy-prostan-1-oic acid. CAS Number:...
Keywords: | 13,14-dihydro-19(R)-hydroxy PGE1, 19(R)-hydroxy PGE0, 9-oxo-11alpha,15S,19R-trihydroxy-prostan-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 2108853-39-8 |
MW: | 372.5 D |
From 143.00€
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Item number: Cay13360-10
Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 µg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2alpha.Formal Name:...
Keywords: | 8-epi PGE1, 8-iso PGE1, Ovinonic acid, 9-oxo-11alpha,15S-dihydroxy-(8beta)-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 21003-46-3 |
MW: | 354.5 D |
From 69.00€
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Item number: Cay13600-50
The Aurora kinases (A, B, and C) are a family of serine-threonine kinases that regulate various stages of mitotic function. With significant roles in cell cycle and cell division, Aurora kinase gene amplification and overexpression are linked to tumorigenesis. MK-0457 is a potent pan-Aurora kinase inhibitor but...
Keywords: | Tozasertib, VX-680,... |
Application: | Aurora kinase inhibitor |
CAS | 639089-54-6 |
MW: | 464.6 D |
From 115.00€
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Item number: Cay13667-10
The amino acid gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that acts through two families of heteromeric ligand-gated ion channels, GABAA and GABAC and a G protein-coupled receptor, GABAB. Muscimol is a full GABAA agonist and partial GABAC agonist. It binds GABAA on both high- and low-affinity...
Keywords: | Agarin, Pantherine, 5-(aminomethyl)-3(2H)-isoxazolone |
Application: | GABAA agonist |
CAS | 2763-96-4 |
MW: | 114.1 D |
From 98.00€
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Item number: Cay13668-10
Fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mediate the hydrolysis of the endocannabinoids arachidonoyl ethanolamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively. JZL 195 is a potent inhibitor of both FAAH and MAGL (IC50s = 2 and 4 nM, respectively). It poorly inhibits neuropathy...
Keywords: | 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate |
Application: | FAAH / MAGL inhibitor |
CAS | 1210004-12-8 |
MW: | 433.5 D |
From 82.00€
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Item number: Cay13664-10
Autotaxin is a lysophospholipase D, cleaving lysophosphatidylcholine to produce choline and lysophosphatidic acid (LPA). S32826 is a potent and selective inhibitor of autotaxin, inhibiting recombinant autotaxin beta with an IC50 of 8.8 nM. It shows similar effectiveness against the three known autotaxin isoforms...
Keywords: | P-[[4-[(1-oxotetradecyl)amino]phenyl]methyl]-phosphonic acid |
Application: | Autotaxin inhbitor |
CAS | 1096770-84-1 |
MW: | 397.5 D |
From 52.00€
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Item number: Cay13665-10
Microsomal prostaglandin E2 synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever, and pain. 5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs), which are pro-inflammatory mediators. YS-121 is a dual inhibitor of...
Keywords: | 2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-octanoic acid |
Application: | mPGES-1/5-LO inhibitor |
CAS | 916482-17-2 |
MW: | 408 D |
From 74.00€
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Item number: Cay13662-250
Arecoline is a natural alkaloid that is found in the betel nut of the Areca palm. It is an agonist of the muscarinic acetylcholine receptors with EC50 values of 7, 95, 11, 410, and 69 nM for M1, M2, M3, M4, and M5, respectively. Generally, arecoline causes smooth muscle contraction. Arecoline and other muscarinic...
Keywords: | 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylic acid, methyl ester, monohydrobromide |
Application: | Muscarinic acetylcholine receptor agonist |
CAS | 300-08-3 |
MW: | 236.1 D |
From 26.00€
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